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Gene Expression Data
Assay Details
Assay
Reference: J:149237 Perez-Balaguer A, et al., Shh dependent and independent maintenance of basal midbrain. Mech Dev. 2009 May-Jun;126(5-6):301-13
Assay type: RNA in situ
MGI Accession ID: MGI:6304438
Gene symbol: Wnt1
Gene name: wingless-type MMTV integration site family, member 1
Probe: Wnt1 probe30
Probe preparation: Antisense RNA
Results
Specimen 3I: embryonic day 10.5 (more )
Note: Double labeled: red - Wnt1; blue - Shh (assay MGI:6304335).
Structure Level Pattern Image Note
TS17: midbrain roof plate Present 3I
TS17: midbrain-hindbrain junction Present 3I
Specimen 3J: embryonic day 10.5; Shhtm2Amc/Shhtm2Amc, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant. Double labeled: red - Wnt1; blue - Shh (assay MGI:6304335).
Structure Level Pattern Image Note
TS17: midbrain roof plate Present 3J Normal expression was detected in the mutant.
TS17: midbrain-hindbrain junction Present 3J Normal expression was detected in the mutant.
Specimen 3K: embryonic day 12.5 (more )
Note: Double labeled: red - Wnt1; blue - Shh (assay MGI:6304335).
Structure Level Pattern Image Note
TS20: midbrain roof plate Present 3K
TS20: midbrain-hindbrain junction Present 3K
Specimen 3L: embryonic day 12.5; Shhtm2Amc/Shhtm2Amc, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant. Double labeled: red - Wnt1; blue - Shh (assay MGI:6304335).
Structure Level Pattern Image Note
TS20: midbrain roof plate Present 3L Normal expression was detected in the mutant.
TS20: midbrain-hindbrain junction Present 3L Expression was detected normally, but the isthmic ring is clearly reduced at E12.5 in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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