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Gene Expression Data
Assay Details
Assay
Reference: J:149237 Perez-Balaguer A, et al., Shh dependent and independent maintenance of basal midbrain. Mech Dev. 2009 May-Jun;126(5-6):301-13
Assay type: RNA in situ
MGI Accession ID: MGI:6304437
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe84
Probe preparation: Antisense RNA
Results
Specimen 3E: embryonic day 10.5 (more )
Note: Double labeled: red - Fgf8; blue - Shh (assay MGI:6304335).
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present 3E
Specimen 3F: embryonic day 10.5; Shhtm2Amc/Shhtm2Amc, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant. Double labeled: red - Fgf8; blue - Shh (assay MGI:6304335).
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present 3F Normal expression was detected in the mutant.
Specimen 3G: embryonic day 12.5 (more )
Note: Double labeled: red - Fgf8; blue - Shh (assay MGI:6304335).
Structure Level Pattern Image Note
TS20: midbrain-hindbrain junction Present 3G
Specimen 3H: embryonic day 12.5; Shhtm2Amc/Shhtm2Amc, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant. Double labeled: red - Fgf8; blue - Shh (assay MGI:6304335).
Structure Level Pattern Image Note
TS20: midbrain-hindbrain junction Present 3H Expression was detected normally, but the isthmic ring is clearly reduced at E12.5 in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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