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Gene Expression Data
Assay Details
Assay
Reference: J:206581 Bowles J, et al., Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo. Dev Biol. 2014 Feb 1;386(1):25-33
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6303623
Gene symbol: Lyve1
Gene name: lymphatic vessel endothelial hyaluronan receptor 1
Antibody: anti-LYVE-1
Results
Specimen 3D: embryonic day 11.5 (more )
Note: Triple labeled: red - Lyve1; green - Pdpn (assay MGI:6303622); blue -Pecam1 (assay MGI:6303623).
Structure Level Pattern Image Note
TS19: cardinal vein Present Regionally restricted 3D Expression in LEC progenitors organized along the anterior-posterior axis of the cardinal vein.
Specimen 3E: embryonic day 11.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Note: Triple labeled: red - Lyve1; green - Pdpn (assay MGI:6303622); blue -Pecam1 (assay MGI:6303623).
Structure Level Pattern Image Note
TS19: cardinal vein Present Regionally restricted 3E Authors report aberrant distribution of LEC progenitors in wall of cardinal vein of mutants compared to wild type.
Specimen 3F/H: embryonic day 11.5 (more )
Note: Double labeled: blue - Lyve1; red - Prox1 (assay MGI:6303621).
Structure Level Pattern Image Note
TS19: lymph sac Present 3H , 3F
Specimen 3I/K: embryonic day 11.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Note: Double labeled: blue - Lyve1; red - Prox1 (assay MGI:6303621).
Structure Level Pattern Image Note
TS19: lymph sac Present Regionally restricted 3I , 3K Authors report enlarged lymph sacs in mutatnt embryos complared to wild type embryos.
Specimen 4I: embryonic day 14.5 (more )
Note: Triple labeled: red - Lyve1; green - Pdpn (assay MGI:6303622); blue -Pecam1 (assay MGI:6303623).
Structure Level Pattern Image Note
TS22: lymph sac Present 4I
Specimen 4J: embryonic day 14.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Note: Triple labeled: red - Lyve1; green - Pdpn (assay MGI:6303622); blue -Pecam1 (assay MGI:6303623).
Structure Level Pattern Image Note
TS22: lymph sac Present Regionally restricted 4J Authors report enlarge lymph sacs in mutatnt embryos complared to wild type embryos.
Specimen 5E/F: embryonic day 13.5 (more )
Note: Triple labeled: blue - Lyve1; green - Foxc2 (assay MGI:6303625); red - Prox1 (assay MGI:6303621).
Structure Level Pattern Image Note
TS21: lymph sac Present 5F , 5E
Specimen 5I/J: embryonic day 13.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Note: Triple labeled: blue - Lyve1; green - Foxc2 (assay MGI:6303625); red - Prox1 (assay MGI:6303621).
Structure Level Pattern Image Note
TS21: lymph sac Present 5J , 5I
Specimen 6C: embryonic day 14.5 (more )
Note: Triple labeled: red - Lyve1; green - Pdpn (assay MGI:6303622); blue -Pecam1 (assay MGI:6303623).
Structure Level Pattern Image Note
TS22: lymph sac Present 6C
Specimen S2C: embryonic day 11.5 (more )
Note: Triple labeled: red - Lyve1; green - Pdpn (assay MGI:6303622); blue -Pecam1 (assay MGI:6303623).
Structure Level Pattern Image Note
TS19: cardinal vein Present S2C
Specimen S2D: embryonic day 11.5; Cyp26b1tm1Hmd/Cyp26b1tm1Hmd (more )
Note: Triple labeled: red - Lyve1; green - Pdpn (assay MGI:6303622); blue -Pecam1 (assay MGI:6303623).
Structure Level Pattern Image Note
TS19: cardinal vein Present Regionally restricted S2D Authors report ectopic distribution of LEC precursors throughout both dorso-lateral and ventro-medial aspects of cardinal vein.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory