Pdpn Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:206581 Bowles J, et al., Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo. Dev Biol. 2014 Feb 1;386(1):25-33
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6303622
Gene symbol:	Pdpn
Gene name:	podoplanin

Antibody:

Results

3A ©

Specimen 3A: embryonic day 11.5 (more

)
Note: Double labeled: green - Pdpn; red - Prox1 (assay MGI:6303621).

Structure	Level	Pattern	Image	Note
TS19: cardinal vein	Ambiguous	Regionally restricted	3A	No expression in lymphatic endothelial cell (LEC) progenitors.

3B ©

Specimen 3B: embryonic day 11.5; Cyp26b1^tm1Hmd/Cyp26b1^tm1Hmd (more

)
Note: Double labeled: green - Pdpn; red - Prox1 (assay MGI:6303621).

Structure	Level	Pattern	Image	Note
TS19: cardinal vein	Present	Regionally restricted	3B	No expression in lymphatic endothelial cell (LEC) progenitors.

3D ©

Specimen 3D: embryonic day 11.5 (more

)
Note: Triple labeled: green - Pdpn; red - Lyve1 (assay MGI:6303623); blue -Pecam1 (assay MGI:6303623).

Structure	Level	Pattern	Image	Note
TS19: cardinal vein	Ambiguous	Regionally restricted	3D	No expression in lymphatic endothelial cell (LEC) progenitors.

3E ©

Specimen 3E: embryonic day 11.5; Cyp26b1^tm1Hmd/Cyp26b1^tm1Hmd (more

)
Note: Triple labeled: green - Pdpn; red - Lyve1 (assay MGI:6303623); blue -Pecam1 (assay MGI:6303623).

Structure	Level	Pattern	Image	Note
TS19: cardinal vein	Ambiguous	Regionally restricted	3E	No expression in lymphatic endothelial cell (LEC) progenitors.

4I ©

Specimen 4I: embryonic day 14.5 (more

)
Note: Triple labeled: green - Pdpn; red - Lyve1 (assay MGI:6303623); blue -Pecam1 (assay MGI:6303623).

Structure	Level	Pattern	Image	Note
TS22: lymph sac	Present		4I
TS22: spinal cord	Present	Regionally restricted	4I	Authors state expressing cells on medial side of jugular vein correspond to undifferentiated neurons in the neural tube.

4J ©

Specimen 4J: embryonic day 14.5; Cyp26b1^tm1Hmd/Cyp26b1^tm1Hmd (more

)
Note: Triple labeled: green - Pdpn; red - Lyve1 (assay MGI:6303623); blue -Pecam1 (assay MGI:6303623).

Structure	Level	Pattern	Image	Note
TS22: lymph sac	Present	Regionally restricted	4J	Authors report enlarge lymph sacs in mutatnt embryos complared to wild type embryos.

6C ©

Specimen 6C: embryonic day 14.5 (more

)
Note: Triple labeled: green - Pdpn; red - Lyve1 (assay MGI:6303623); blue -Pecam1 (assay MGI:6303623).

Structure	Level	Pattern	Image	Note
TS22: lymph sac	Present		6C

6E ©

Specimen 6E: embryonic day 14.5 (more

)
Note: Triple labeled: green - Pdpn; red - Prox1 (assay MGI:6303621); blue -Pecam1 (assay MGI:6303623).

Structure	Level	Pattern	Image	Note
TS22: lymph sac	Present		6E

S2C ©

Specimen S2C: embryonic day 11.5 (more

)
Note: Triple labeled: green - Pdpn; red - Lyve1 (assay MGI:6303623); blue -Pecam1 (assay MGI:6303623).

Structure	Level	Pattern	Image	Note
TS19: cardinal vein	Present		S2C

S2D ©

Specimen S2D: embryonic day 11.5; Cyp26b1^tm1Hmd/Cyp26b1^tm1Hmd (more

)
Note: Triple labeled: green - Pdpn; red - Lyve1 (assay MGI:6303623); blue -Pecam1 (assay MGI:6303623).

Structure	Level	Pattern	Image	Note
TS19: cardinal vein	Present	Regionally restricted	S2D	Authors report ectopic distribution of LEC precursors throughout both dorso-lateral and ventro-medial aspects of cardinal vein.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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