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Gene Expression Data
Assay Details
Assay
Reference: J:163555 Huang CC, et al., Inactivation of Dicer1 in Steroidogenic factor 1-positive cells reveals tissue-specific requirement for Dicer1 in adrenal, testis, and ovary. BMC Dev Biol. 2010;10:66
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6296593
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67
Assay notes: Controls (CT) were either Dicer1 flox/flox (homozygous) or Dicer1 flox/+ (heterozygous) littermate embryos.
Results
Specimen 1C 16.5 dpc CT: embryonic day 16.5; Dicer1tm1Bdh/Dicer1tm1Bdh (more )
Note: Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS24: adrenal cortex Present 1C 16.5 dpc CT
Specimen 1C 16.5 dpc KO: embryonic day 16.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS24: adrenal cortex Present 1C 16.5 dpc KO Authors report no apparent changes in the number of expressing cells in mutant cortex compared to control.
Specimen 1C 18.5 dpc CT: embryonic day 18.5; Dicer1tm1Bdh/Dicer1tm1Bdh (more )
Note: Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS26: adrenal cortex Present 1C 18.5 dpc CT
Specimen 1C 18.5 dpc KO: embryonic day 18.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS26: adrenal cortex Present 1C 18.5 dpc KO Authors report no apparent changes in the number of expressing cells in mutant cortex compared to control.
Specimen 1C P0 CT: postnatal day 0; Dicer1tm1Bdh/Dicer1tm1Bdh (more )
Note: Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS27: adrenal cortex Present 1C P0 CT
Specimen 1C P0 KO: postnatal day 0; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS27: adrenal cortex Present 1C P0 KO Authors report no apparent changes in the number of expressing cells in mutant cortex compared to control.
Specimen 1C P5 CT: postnatal day 5; Dicer1tm1Bdh/Dicer1tm1Bdh (more )
Note: Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS28: adrenal cortex Present 1C P5 CT
Specimen 1C P5 KO: postnatal day 5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS28: adrenal cortex Present 1C P5 KO Authors report no apparent changes in the number of expressing cells in mutant cortex compared to control.
Specimen 5B P0 CT: postnatal day 0; Dicer1tm1Bdh/Dicer1tm1Bdh (more )
Note: Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS27: testis Present 5B P0 CT
Specimen 5B P0 KO: postnatal day 0; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS27: testis Present 5B P0 KO
Specimen 5B P2 CT: postnatal day 2; Dicer1tm1Bdh/Dicer1tm1Bdh (more )
Note: Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS27: testis Present 5B P2 CT
Specimen 5B P2 KO: postnatal day 2; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS27: testis Present 5B P2 KO
Specimen 5B P5 CT: postnatal day 5; Dicer1tm1Bdh/Dicer1tm1Bdh (more )
Note: Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS28: testis Present 5B P5 CT
Specimen 5B P5 KO: postnatal day 5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS28: testis Present 5B P5 KO
Specimen 7A CT: postnatal day 5; Dicer1tm1Bdh/Dicer1tm1Bdh (more )
Note: Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS28: ovary Present 7A CT
Specimen 7A KO: postnatal day 5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Triple labeled: green - Mki67; red - Hsd3b (assay MGI:6296592); blue - DAPI.
Structure Level Pattern Image Note
TS28: ovary Present 7A KO Authors state expression patterns were indistinguishable between mutant control embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory