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Gene Expression Data
Assay Details
Assay
Reference: J:178483 Berbari NF, et al., Mutations in Traf3ip1 reveal defects in ciliogenesis, embryonic development, and altered cell size regulation. Dev Biol. 2011 Dec 1;360(1):66-76
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6280942
Gene symbol: Ptch1
Gene name: patched 1
Reporter: lacZ
Direct Detection
Results
Specimen 6A: embryonic day 10.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS17: embryo Present 6A
Specimen 6B: embryonic day 10.5; Ptch1tm1Mps/Ptch1+, Traf3ip1Gt(RRJ005)Byg/Traf3ip1Gt(RRJ005)Byg (more )
Structure Level Pattern Image Note
TS17: embryo Present Regionally restricted 6B Authors report a similar pattern of expression to that of wild type embryos.
Specimen 6C: embryonic day 10.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS17: gut Present 6C
TS17: neural tube Present 6C
Specimen 6D: embryonic day 10.5; Ptch1tm1Mps/Ptch1+, Traf3ip1Gt(RRJ005)Byg/Traf3ip1Gt(RRJ005)Byg (more )
Structure Level Pattern Image Note
TS17: gut Weak 6D Authors report much reduced expression in both neural and endoderm tubes compared to that of wildtype.
TS17: neural tube Weak 6D Authors report much reduced expression in both neural and endoderm tubes compared to that of wildtype.
Specimen 6E: embryonic day 10.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS17: tail neural tube Present 6E
Specimen 6F: embryonic day 10.5; Ptch1tm1Mps/Ptch1+, Traf3ip1Gt(RRJ005)Byg/Traf3ip1Gt(RRJ005)Byg (more )
Structure Level Pattern Image Note
TS17: tail neural tube Absent 6F Authors state expression in caudal neural tube is nearly absent.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory