Gene Expression Data
Assay Details
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Assay
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Reference:
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J:166613
Cao H, et al., Tbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21. Dev Biol. 2010 Nov 15;347(2):289-300
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6273808
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Gene symbol:
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Cdkn1a
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Gene name:
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cyclin dependent kinase inhibitor 1A
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Antibody:
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anti-p21
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
5A:
embryonic day 16.5
(more  )
Specimen
5A:
(close  )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: molar epithelium |
Weak |
Widespread |
5A
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Low expression ithroughout the dental epithelium.
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Specimen
5B:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1tm1Bld
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: molar epithelium |
Present |
Widespread |
5B
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Increased expression throughout dental epithelium.
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Specimen
5C:
embryonic day 18.5
(more )
Specimen
5C:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: molar epithelium |
Weak |
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5C
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Authors report minimal expression in dental epithelium.
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Specimen
5D:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1tm1Bld
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: molar epithelium |
Strong |
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5D
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Increased expression in dental epithelium compared to that of Tbx-/- E16.5 molars and E18.5 wild-type molars.
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Analysis Tools
