Bcl11a In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:237333 Dias C, et al., BCL11A Haploinsufficiency Causes an Intellectual Disability Syndrome and Dysregulates Transcription. Am J Hum Genet. 2016 Aug 04;99(2):253-74
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:6272870
Gene symbol:	Bcl11a
Gene name:	BCL11 transcription factor A

Reporter:	lacZ
	Direct Detection

Results

S1B ©

Specimen S1B: embryonic day 12.5; Bcl11a^tm3Peli/Bcl11a⁺ (more

)

Structure	Level	Image
TS20: forebrain	Strong	S1B
TS20: hindbrain	Strong	S1B
TS20: spinal cord	Strong	S1B
TS20: limb	Present	S1B
TS20: mandibular process	Present	S1B
TS20: maxillary process	Present	S1B
TS20: somite	Present	S1B

S1C ©

Specimen S1C: embryonic day 14.5; Bcl11a^tm3Peli/Bcl11a⁺ (more

)

Structure	Level	Image
TS22: forebrain	Strong	S1C
TS22: hindbrain	Strong	S1C
TS22: midbrain	Strong	S1C
TS22: midbrain-hindbrain junction	Strong	S1C
TS22: pinna	Strong	S1C

S1D ©

Specimen S1D: postnatal adult; Bcl11a^tm3Peli/Bcl11a⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: accumbens nucleus	Strong		S1D
TS28: cerebral cortex	Strong		S1D
TS28: hippocampus	Strong		S1D
TS28: main olfactory bulb	Strong		S1D
TS28: olfactory tubercle	Strong		S1D
TS28: cerebellum Purkinje cell layer	Present		S1D
TS28: thalamus	Present		S1D
TS28: pons	Present	Regionally restricted	S1D	Expressed in a restricted area on the ventral aspect.

Specimen not shown: embryonic day 10.5; Bcl11a^tm3Peli/Bcl11a⁺ (more

)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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