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Bcl11atm3Peli
Targeted Allele Detail
Summary
Symbol: Bcl11atm3Peli
Name: BCL11 transcription factor A; targeted mutation 3, Pentao Liu
MGI ID: MGI:5787772
Synonyms: Bcl11a-lacZ
Gene: Bcl11a  Location: Chr11:24028056-24124123 bp, + strand  Genetic Position: Chr11, 14.41 cM
Alliance: Bcl11atm3Peli page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:219746
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsAn SA-IRES-lacZ cassette with a 3' loxP site was inserted into intron 3. An F3 site-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 4. (J:219746, J:237333)
Expression
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl11a Mutation:  42 strains or lines available
References
Original:  J:219746 Khaled WT, et al., BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells. Nat Commun. 2015;6:5987
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory