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Gene Expression Data
Assay Details
Assay
Reference: J:44409 Gofflot F, et al., Genetic patterning of the developing mouse tail at the time of posterior neuropore closure. Dev Dyn. 1997 Dec;210(4):431-45
Assay type: RNA in situ
MGI Accession ID: MGI:6231157
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe82
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2J: embryonic day 10.5 (more )
Note: 28-30 somite stage.
Structure Level Pattern Image Note
TS17: tail Present Regionally restricted 2J Expression was detected in a very small area at the tip of the tail, including the dorsal half of the tail bud and the condensing prenotochordal cells.
TS17: neural tube Present Regionally restricted 2J Expression was at the tip of the tail in the neural plate/tube.
TS17: hindgut Present Regionally restricted 2J Expression was detected at the caudal end of the hindgut.
Specimen 3a: embryonic day 10.5 (more )
Note: Fig. 3 sections are presented in a caudal to cranial sequence (a-e).
Structure Level Pattern Image Note
TS17: tail Present Regionally restricted 3_Fgf8 a Expression was detected in the dorsal half of the tail bud.
Specimen 3b: embryonic day 10.5 (more )
Note: Fig. 3 sections are presented in a caudal to cranial sequence (a-e).
Structure Level Pattern Image Note
TS17: hindgut Present 3_Fgf8 b
TS17: notochord Present 3_Fgf8 b
TS17: future spinal cord Strong Regionally restricted 3_Fgf8 b Expression was high in the neural plate.
TS17: tail mesenchyme Weak Diffuse 3_Fgf8 b
Specimen 3c: embryonic day 10.5 (more )
Note: Fig. 3 sections are presented in a caudal to cranial sequence (a-e).
Structure Level Pattern Image Note
TS17: hindgut Present 3_Fgf8 c
TS17: neural tube Present Regionally restricted 3_Fgf8 c
TS17: neural tube roof plate Absent 3_Fgf8 c
TS17: tail mesenchyme Weak Diffuse 3_Fgf8 c At this section, expression began to be lost in a ventral to dorsal sequence in progressively more cranial sections.
Specimen 3d: embryonic day 10.5 (more )
Note: Fig. 3 sections are presented in a caudal to cranial sequence (a-e).
Structure Level Pattern Image Note
TS17: tail mesenchyme Weak Diffuse 3_Fgf8 d Expression began to be lost in a ventral to dorsal sequence in progressively more cranial sections.
Specimen 3e: embryonic day 10.5 (more )
Note: Fig. 3 sections are presented in a caudal to cranial sequence (a-e).
Structure Level Pattern Image Note
TS17: tail Ambiguous 3_Fgf8 e
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory