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Gene Expression Data
Assay Details
Assay
Reference: J:44409 Gofflot F, et al., Genetic patterning of the developing mouse tail at the time of posterior neuropore closure. Dev Dyn. 1997 Dec;210(4):431-45
Assay type: RNA in situ
MGI Accession ID: MGI:6226146
Gene symbol: T
Gene name: brachyury, T-box transcription factor T
Probe: Brachyury probe21
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2H: embryonic day 10.5 (more )
Note: 28-30 somite stage.
Structure Level Pattern Image Note
TS17: tail Very strong 2H Very strong expression was detected in the tail bud and epiblast.
TS17: tail mesenchyme Very strong Regionally restricted 2H Very strong expression was detected in the gastrulating mesoderm.
TS17: hindgut Very strong Regionally restricted 2H Very strong expression was detected in the most caudal hindgut.

Specimen 3a: embryonic day 10.5 (more )
Note: Fig. 3 sections are presented in a caudal to cranial sequence (a-e).
Structure Level Pattern Image Note
TS17: tail Present 3_Brachyury a

Specimen 3b: embryonic day 10.5 (more )
Note: Fig. 3 sections are presented in a caudal to cranial sequence (a-e).
Structure Level Pattern Image Note
TS17: tail Present Regionally restricted 3_Brachyury b In the tail bud and where the caudal neuropore is open, only the surface ectoderm is unlabeled.
TS17: tail surface ectoderm Absent 3_Brachyury b
TS17: future spinal cord Strong Uniform 3_Brachyury b In the neuropore, the actively curving neuroepithelium shows a high and uniform level of expression.

Specimen 3c: embryonic day 10.5 (more )
Note: Fig. 3 sections are presented in a caudal to cranial sequence (a-e).
Structure Level Pattern Image Note
TS17: notochord Present 3_Brachyury c

Specimen 3d: embryonic day 10.5 (more )
Note: Fig. 3 sections are presented in a caudal to cranial sequence (a-e).
Structure Level Pattern Image Note
TS17: notochord Present 3_Brachyury d
TS17: neural tube Present Non-Uniform 3_Brachyury d Expression was more intense in the median and lateral hinge points.
TS17: tail paraxial mesenchyme Present Regionally restricted 3_Brachyury d Expression was restricted to the dorsal paraxial mesenchyme.

Specimen 3e: embryonic day 10.5 (more )
Note: Fig. 3 sections are presented in a caudal to cranial sequence (a-e).
Structure Level Pattern Image Note
TS17: notochord Present 3_Brachyury e


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory