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Gene Expression Data
Assay Details
Assay
Reference: J:260088 Ueda T, et al., Basal cells express functional TRPV4 channels in the mouse nasal epithelium. Biochem Biophys Rep. 2015 Dec;4:169-174
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6202588
Gene symbol: Trpv4
Gene name: transient receptor potential cation channel, subfamily V, member 4
Antibody: anti-TRPV4
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 2A: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: olfactory epithelium Present Regionally restricted 2A Expression in basal layers of olfactory epithelium.
TS27: nasal septum cartilage Present Regionally restricted 2A Expression in cartilage surrounding nasal cavity.
Specimen 2B: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: nasal cavity respiratory epithelium Present Regionally restricted 2B Expression in basal layers of ciliated airway epithelium.
TS27: nasal cavity epithelium Present Regionally restricted 2B Expression in basal layers of squamous epithelium.
Specimen 2C: postnatal day 2; Trpv4tm1Msz/Trpv4tm1Msz (more )
Structure Level Pattern Image Note
TS27: olfactory epithelium Absent 2C No expression in basal layers of olfactory epithelium .
TS27: nasal septum cartilage Ambiguous 2C No expression in cartilage surrounding nasal cavity.v
Specimen 2D: postnatal day 2; Trpv4tm1Msz/Trpv4tm1Msz (more )
Structure Level Pattern Image Note
TS27: nasal cavity respiratory epithelium Absent 2D No expression in basal layers of ciliated airway epithelium.
TS27: nasal cavity epithelium Ambiguous 2D No expression in basal layers of squamous epithelium.
Specimen 2E: postnatal day 8 (more )
Note: Double labeled: red - Trpv4; green - keratin.
Structure Level Pattern Image Note
TS28: nasal cavity respiratory epithelium Present Regionally restricted 2E Merged , 2E TRPV4 Authors report expression co-localized with Krt14 immunoreactivity in most basal cells in airway epithelium.
Specimen 2F: postnatal day 8 (more )
Note: Double labeled: red - Trpv4; green - keratin.
Structure Level Pattern Image Note
TS28: olfactory epithelium Present Regionally restricted 2F Merged , 2F TRPV4 Expression overlapped with Krt14 in a subset of horizontal basal cells (HBCs) near boundary with airway epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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