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Gene Expression Data
Assay Details
Assay
Reference: J:57646 Wigle JT, et al., Prox1 function is required for the development of the murine lymphatic system. Cell. 1999 Sep 17;98(6):769-78
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6201329
Gene symbol: Prox1
Gene name: prospero homeobox 1
Reporter: lacZ
Antibody: anti-B-galactosidase (55976)
Detection system: Secondary antibody
Results
Specimen 2B: embryonic day 10.5; Prox1tm1Gco/Prox1+ (more )
Structure Level Pattern Image Note
TS17: cardiovascular system endothelium Present Regionally restricted 2B Expression in endothelial cells budding from anterior cardinal vein - represented only a subpopulation of endothelial cells.

Specimen 3A: embryonic day 12.5; Prox1tm1Gco/Prox1+ (more )
Structure Level Pattern Image Note
TS20: cardinal vein Present Regionally restricted 3A Expression in cells in wall of cardinal vein.
TS20: cardiovascular system endothelium Present Regionally restricted 3A Expression in cells budding out from the vein.

Specimen 6A: embryonic day 10.5; Prox1tm1Gco/Prox1+ (more )
Structure Level Pattern Image Note
TS17: cardiovascular system endothelium Present Regionally restricted 6A Authors report no obvious differences in number of expressing endothelial cells lining wall of anterior cardinal vein between Prox+/- and Prox1-/- littermates.

Specimen 6C: embryonic day 10.5; Prox1tm1Gco/Prox1tm1Gco (more )
Structure Level Pattern Image Note
TS17: cardiovascular system endothelium Present Regionally restricted 6C Authors report no obvious differences in number of expressing endothelial cells lining wall of anterior cardinal vein between Prox+/- and Prox1-/- littermates.

Specimen 6E: embryonic day 12.5; Prox1tm1Gco/Prox1+ (more )
Structure Level Pattern Image Note
TS20: cardiovascular system endothelium Present Regionally restricted 6E Expression in endothelial cells in the vicinity of the cardinal vein.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory