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Gene Expression Data
Assay Details
Assay
Reference: J:192680 Quina LA, et al., Deletion of a conserved regulatory element required for Hmx1 expression in craniofacial mesenchyme in the dumbo rat: a newly identified cause of congenital ear malformation. Dis Model Mech. 2012 Nov;5(6):812-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6200086
Gene symbol: Hmx1
Gene name: H6 homeobox 1
Antibody: anti-Hmx1
Detection system: Secondary antibody
Results
Specimen 6B: embryonic day 12.5; Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Sections at the level of the diencephalon. Double labeled: red - Hmx1; green - Cre reporter.
Structure Level Pattern Image Note
TS20: head mesenchyme derived from neural crest Absent 6B
TS20: mesenchyme derived from head mesoderm Present 6B In the most dorsal and rostral domain of expression, at the level of the diencephalon, positive cells were derived entirely from mesoderm.
Specimen 6C: embryonic day 12.5; Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. More ventral and caudal sections. Double labeled: red - Hmx1; green - Cre reporter.
Structure Level Pattern Image Note
TS20: head mesenchyme derived from neural crest Present 6C
TS20: mesenchyme derived from head mesoderm Present 6C
Specimen 6D: embryonic day 12.5; Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. More ventral and caudal sections. Double labeled: red - Hmx1; green - Cre reporter.
Structure Level Pattern Image Note
TS20: head mesenchyme derived from neural crest Present 6D
TS20: mesenchyme derived from head mesoderm Present 6D
Specimen 6E: embryonic day 12.5; Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. More ventral and caudal sections. Double labeled: red - Hmx1; green - Cre reporter.
Structure Level Pattern Image Note
TS20: head mesenchyme derived from neural crest Present 6E
TS20: mesenchyme derived from head mesoderm Present 6E
Specimen 6F: embryonic day 12.5; Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. More ventral and caudal sections. Double labeled: red - Hmx1; green - Cre reporter.
Structure Level Pattern Image Note
TS20: head mesenchyme derived from neural crest Present 6F
TS20: mesenchyme derived from head mesoderm Present 6F Expressed predominantly in this mesoderm-derived craniofacial mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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