About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:105155 Semba K, et al., A Novel Murine Gene, Sickle tail, Linked to the Danforth's short tail Locus, Is Required for Normal Development of the Intervertebral Disc. Genetics. 2006 Jan;172(1):445-56
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6195736
Gene symbol: Etl4
Gene name: enhancer trap locus 4
Reporter: lacZ
Direct Detection
Assay notes: Fix - 1% formaldehyde, 0.2% glutaraldehyde.
Results
Specimen 4A: embryonic day 7.5; Etl4Gt(pU8)80211Imeg/Etl4+ (more )
Structure Level Pattern Image Note
TS11: chorion Present 4A
TS11: embryo Absent 4A
Specimen 4B: embryonic day 8.5; Etl4Gt(pU8)80211Imeg/Etl4+ (more )
Structure Level Pattern Image Note
TS13: notochord Strong 4B
Specimen 4C: embryonic day 9.0; Etl4Gt(pU8)80211Imeg/Etl4+ (more )
Structure Level Pattern Image Note
TS14: notochord Strong 4C
Specimen 4D: embryonic day 11.5; Etl4Gt(pU8)80211Imeg/Etl4+ (more )
Structure Level Pattern Image Note
TS19: mesonephros Strong 4D
TS19: notochord Strong 4D
Specimen 4E: embryonic day 11.5; Etl4Gt(pU8)80211Imeg/Etl4+ (more )
Structure Level Pattern Image Note
TS19: mesonephros Strong 4E
TS19: notochord Strong 4E
Specimen 4F: embryonic day 11.5; Etl4Gt(pU8)80211Imeg/Etl4+ (more )
Structure Level Pattern Image Note
TS19: mesonephros Strong 4F
TS19: notochord Strong 4F
Specimen not shown: embryonic day 11.5; Etl4Gt(pU8)80211Imeg/Etl4+ (more )
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted Expression was detected in the epithalamus sulcus and the infundibulum.
TS19: telencephalon Present Regionally restricted Expression was detected in the roof of the neopallial cortex.
TS19: retina Present Regionally restricted Expression was detected in the inner layer of retina.
TS19: liver Present Regionally restricted Expression was detected in the surface of hepatic primordium.
TS19: heart atrium Present
TS19: heart ventricle Present
TS19: hindgut Present
TS19: lens vesicle Present
TS19: limb mesenchyme Present
TS19: surface ectoderm Present
Specimen 4K: postnatal newborn; Etl4Gt(pU8)80211Imeg/Etl4+ (more )
Structure Level Pattern Image Note
TS27: nucleus pulposus Present Regionally restricted 4L , 4K X-gal-positive cells were positioned in the center of the vertebrae.
Specimen 4M: postnatal newborn; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg (more )
Structure Level Pattern Image Note
TS27: nucleus pulposus Present Regionally restricted 4M , 4N X-gal-positive cells in the nucleus pulposus were shifted to the periphery in the mutant.
Specimen 4O: postnatal week 2; Etl4Gt(pU8)80211Imeg/Etl4+ (more )
Structure Level Pattern Image Note
TS28: nucleus pulposus Present Regionally restricted 4O , 4P X-gal-positive cells were positioned in the center of the vertebrae.
Specimen 4Q: postnatal week 2; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg (more )
Structure Level Pattern Image Note
TS28: nucleus pulposus Present Regionally restricted 4R , 4Q X-gal-positive cells were dislocated to the left or right side in the mutant.
Specimen not shown: postnatal adult; Etl4Gt(pU8)80211Imeg/Etl4Gt(pU8)80211Imeg (more )
Structure Cell Type Level Pattern Image Note
TS28: cardiac muscle tissue Present
TS28: corpus callosum Present
TS28: hair outer root sheath Present
TS28: renal tubule Present
TS28: Sertoli cell Sertoli cell Present
Specimen 7Ca: embryonic day 9.5; Etl4Gt(pU8)80211Imeg/Etl4+, Etn2Sd/Etn2+ (more )
Note: Alleles were trans-heterozygous.
Structure Level Pattern Image Note
TS15: notochord Present 7Ca The expression pattern in the tail notochord was the same in both trans and cis compound heterozygous embryos.
Specimen 7Cb: embryonic day 13.5; Etl4Gt(pU8)80211Imeg/Etl4+, Etn2Sd/Etn2+ (more )
Note: Alleles were trans-heterozygous.
Structure Level Pattern Image Note
TS21: notochord Present 7Cb The expression pattern in the tail notochord was the same in both trans and cis compound heterozygous embryos.
Specimen 7Cc: embryonic day 13.5; Etl4Gt(pU8)80211Imeg/Etl4+, Etn2Sd/Etn2+ (more )
Note: Alleles were trans-heterozygous.
Structure Level Pattern Image Note
TS21: notochord Present 7Cc The expression pattern in the tail notochord was the same in both trans and cis compound heterozygous embryos.
Specimen 7Cd: embryonic day 9.5; Etl4Gt(pU8)80211Imeg/Etl4+, Etn2Sd/Etn2+ (more )
Note: Alleles were cis-heterozygous.
Structure Level Pattern Image Note
TS15: notochord Present 7Cd The expression pattern in the tail notochord was the same in both trans and cis compound heterozygous embryos.
Specimen 7Ce: embryonic day 13.5; Etl4Gt(pU8)80211Imeg/Etl4+, Etn2Sd/Etn2+ (more )
Note: Alleles were cis-heterozygous.
Structure Level Pattern Image Note
TS21: notochord Present 7Ce The expression pattern in the tail notochord was the same in both trans and cis compound heterozygous embryos.
Specimen 7Cf: embryonic day 13.5; Etl4Gt(pU8)80211Imeg/Etl4+, Etn2Sd/Etn2+ (more )
Note: Alleles were cis-heterozygous.
Structure Level Pattern Image Note
TS21: notochord Present 7Cf The expression pattern in the tail notochord was the same in both trans and cis compound heterozygous embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory