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Gene Expression Data
Assay Details
Assay
Reference: J:135997 Nie X, et al., Disruption of Smad4 in neural crest cells leads to mid-gestation death with pharyngeal arch, craniofacial and cardiac defects. Dev Biol. 2008 Apr 15;316(2):417-30
Assay type: RNA in situ
MGI Accession ID: MGI:6193719
Gene symbol: Pax3
Gene name: paired box 3
Probe: Pax3 probe43
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5G: embryonic day 8.5; Smad4tm2.1Cxd/Smad4+ (more )
Structure Level Pattern Image Note
TS13: embryo Present 5G
Specimen 5H: embryonic day 8.5; Smad4tm2.1Cxd/Smad4tm2.1Cxd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: embryo Present 5H Authors report no obvious abnormal expression.
Specimen 7I: embryonic day 10.5; Smad4tm2.1Cxd/Smad4+ (more )
Structure Level Pattern Image Note
TS17: head Present 7I
Specimen 7J: embryonic day 10.5; Smad4tm2.1Cxd/Smad4tm2.1Cxd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component Absent 7J No expression in maxillary and mandibular prominences.
TS17: 1st branchial arch maxillary component Absent 7J No expression in maxillary and mandibular prominences.
Specimen 7K: embryonic day 11.5; Smad4tm2.1Cxd/Smad4+ (more )
Structure Level Pattern Image Note
TS19: head Present 7K
Specimen 7L: embryonic day 11.5; Smad4tm2.1Cxd/Smad4tm2.1Cxd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: mandibular process Absent 7L No expression in maxillary and mandibular prominences.
TS19: maxillary process Absent 7L No expression in maxillary and mandibular prominences.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory