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Gene Expression Data
Assay Details
Assay
Reference: J:135997 Nie X, et al., Disruption of Smad4 in neural crest cells leads to mid-gestation death with pharyngeal arch, craniofacial and cardiac defects. Dev Biol. 2008 Apr 15;316(2):417-30
Assay type: RNA in situ
MGI Accession ID: MGI:6193715
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Probe: Sox9 probe36
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1K: embryonic day 11.5; Smad4tm2.1Cxd/Smad4+ (more )
Structure Level Pattern Image Note
TS19: mandibular process Present 1K Expression in mandibular prominences.
Specimen 1L: embryonic day 11.5; Smad4tm2.1Cxd/Smad4tm2.1Cxd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: mandibular process Present 1L Expression in mandibular prominences.
Specimen 5E: embryonic day 8.5; Smad4tm2.1Cxd/Smad4+ (more )
Structure Level Pattern Image Note
TS13: embryo Present 5E
Specimen 5F: embryonic day 8.5; Smad4tm2.1Cxd/Smad4tm2.1Cxd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: embryo Present 5F Expression in mandibular prominences.
Specimen 6E: embryonic day 9.5; Smad4tm2.1Cxd/Smad4+ (more )
Structure Level Pattern Image Note
TS15: branchial arch Moderate Widespread 6E Moderate expression in all pharyngeal arches and neural crest cell migration streams.
TS15: migrating neural crest Moderate Widespread 6E Moderate expression in all pharyngeal arches and neural crest cell migration streams.
Specimen 6F: embryonic day 9.5; Smad4tm2.1Cxd/Smad4tm2.1Cxd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: migrating neural crest Weak 6F Expression was visibly reduced but not eliminated.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory