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Gene Expression Data
Assay Details
Assay
Reference: J:222431 Cunningham TJ, et al., Wnt8a and Wnt3a cooperate in the axial stem cell niche to promote mammalian body axis extension. Dev Dyn. 2015 Jun;244(6):797-807
Assay type: RNA in situ
MGI Accession ID: MGI:6151398
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 cDNA26
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen WT top: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Strong Regionally restricted 3_WT top Expression is caudal.
Specimen WT bottom: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Strong Regionally restricted 3_WT bottom Expression is caudal.
Specimen Wnt3a+/-;Wnt8a-/- top: embryonic day 8.5; Wnt3atm1Amc/Wnt3a+, Wnt8atm1(KOMP)Vlcg/Wnt8atm1(KOMP)Vlcg (more )
Structure Level Pattern Image Note
TS13: embryo Strong Regionally restricted 3_Wnt3a+/-;Wnt8a-/- top Expression in this mutant is the same as in wild-type embryos.
Specimen Wnt3a+/-;Wnt8a-/- bottom: embryonic day 8.5; Wnt3atm1Amc/Wnt3a+, Wnt8atm1(KOMP)Vlcg/Wnt8atm1(KOMP)Vlcg (more )
Structure Level Pattern Image Note
TS13: embryo Strong Regionally restricted 3_Wnt3a+/-;Wnt8a-/- bottom Expression in this mutant is the same as in wild-type embryos.
Specimen Wnt3a-/-;Wnt8a+/+ top: embryonic day 8.5; Wnt3atm1Amc/Wnt3atm1Amc (more )
Structure Level Pattern Image Note
TS13: embryo Strong Regionally restricted 3_Wnt3a-/-;Wnt8a+/+ top This mutant has a narrowing of the epiblast region and corresponding smaller caudal expression domain.
Specimen Wnt3a-/-;Wnt8a+/+ bottom: embryonic day 8.5; Wnt3atm1Amc/Wnt3atm1Amc (more )
Structure Level Pattern Image Note
TS13: embryo Strong Regionally restricted 3_Wnt3a-/-;Wnt8a+/+ bottom This mutant has a narrowing of the epiblast region and corresponding smaller caudal expression domain.
Specimen Wnt3a-/-;Wnt8a-/- top left: embryonic day 8.5; Wnt3atm1Amc/Wnt3atm1Amc, Wnt8atm1(KOMP)Vlcg/Wnt8atm1(KOMP)Vlcg (more )
Structure Level Pattern Image Note
TS13: embryo Strong Regionally restricted 3_Wnt3a-/-;Wnt8a-/- top left This mutant has an extreme narrowing of the epiblast region and corresponding smaller or no caudal expression domain.
Specimen Wnt3a-/-;Wnt8a-/- bottom left: embryonic day 8.5; Wnt3atm1Amc/Wnt3atm1Amc, Wnt8atm1(KOMP)Vlcg/Wnt8atm1(KOMP)Vlcg (more )
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted 3_Wnt3a-/-;Wnt8a-/- bottom left This mutant has an extreme narrowing of the epiblast region and corresponding smaller or no caudal expression domain.
Specimen Wnt3a-/-;Wnt8a-/- top right: embryonic day 8.5; Wnt3atm1Amc/Wnt3atm1Amc, Wnt8atm1(KOMP)Vlcg/Wnt8atm1(KOMP)Vlcg (more )
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted 3_Wnt3a-/-;Wnt8a-/- top right This mutant has an extreme narrowing of the epiblast region and corresponding smaller or no caudal expression domain.
Specimen Wnt3a-/-;Wnt8a-/- bottom right: embryonic day 8.5; Wnt3atm1Amc/Wnt3atm1Amc, Wnt8atm1(KOMP)Vlcg/Wnt8atm1(KOMP)Vlcg (more )
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted 3_Wnt3a-/-;Wnt8a-/- bottom right This mutant has an extreme narrowing of the epiblast region and corresponding smaller or no caudal expression domain.
Specimen not shown Wnt3a-/-;Wnt8a+/-: embryonic day 8.5; Wnt3atm1Amc/Wnt3atm1Amc, Wnt8atm1(KOMP)Vlcg/Wnt8a+ (more )
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted This mutant has a narrowing of the epiblast region and corresponding smaller caudal expression domain.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory