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Gene Expression Data
Assay Details
Assay
Reference: J:95019 Manley NR, et al., Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. Dev Biol. 2004 Dec 15;276(2):301-12
Assay type: RNA in situ
MGI Accession ID: MGI:6148021
Gene symbol: Gcm2
Gene name: glial cells missing homolog 2
Probe: Gcm2 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6E: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS16: 3rd branchial pouch Present Regionally restricted 6E Expression in presumptive parathyroid anterior-dorsal domain.

Specimen 6F: embryonic day 9.75; Pbx1tm1Mlc/Pbx1tm1Mlc (more )
Structure Level Pattern Image Note
TS16: 3rd branchial pouch Present Diffuse 6F Diffuse expression through majority of third pouch.

Specimen 6G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 3rd branchial pouch Present Regionally restricted 6G Expression in presumptive parathyroid anterior-dorsal domain.

Specimen 6H: embryonic day 10.5; Pbx1tm1Mlc/Pbx1tm1Mlc (more )
Structure Level Pattern Image Note
TS17: 3rd branchial pouch Weak Regionally restricted 6H Expression domain is consistent reduced in intensity compared to wild-type, and is variable in its domain within the third pouch.

Specimen 7F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: thymus/parathyroid primordium Present Regionally restricted 7F Expression marks the parathyroid domains.

Specimen 7G: embryonic day 11.5; Pbx1tm1Mlc/Pbx1tm1Mlc (more )
Structure Level Pattern Image Note
TS19: thymus/parathyroid primordium Weak Regionally restricted 7G Expression domain is smaller than in wildtype embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory