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Gene Expression Data
Assay Details
Assay
Reference: J:54600 Zhang Y, et al., Msx1 is required for the induction of Patched by Sonic hedgehog in the mammalian tooth germ. Dev Dyn. 1999 May;215(1):45-53
Assay type: RNA in situ
MGI Accession ID: MGI:6120860
Gene symbol: Shh
Gene name: sonic hedgehog
Probe: Shh cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component Weak Regionally restricted 2A Expression first detected weakly in the incisor forming region.
Specimen 2D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dental placode Present Regionally restricted 2D Stronger expression in incisor tooth germ. Expression starts to appear in molar tooth germ.
TS19: mandible primordium Present Regionally restricted 2D Stronger expression in incisor tooth germ. Expression starts to appear in molar tooth germ.
Specimen 2G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: jaw primordium epithelium Present Regionally restricted 2G Expression in molar tooth germ, localized to dental epithelium.
Specimen 2J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Present Regionally restricted 2J Expression localized to dental epithelium.
TS20: mandible primordium Present Regionally restricted 2J Expression localized to dental epithelium.
Specimen E13.5 not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: tooth epithelium Present Regionally restricted Expression localized to dental epithelium.
Specimen E14.5 not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: enamel knot Present Expression localized to enamel knot of dental epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory