Thrb RT-PCR Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:208718 Selmi-Ruby S, et al., The targeted inactivation of TRbeta gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production. Endocrinology. 2014 Feb;155(2):635-46
Assay type:	RT-PCR
MGI Accession ID:	MGI:6114674
Gene symbol:	Thrb
Gene name:	thyroid hormone receptor beta

Probe:

Beta e4 primer, Beta e6 primer

Results

Image: 3C left

	Sample Information		Bands		Other Sample Information
Lane	Age	Structure	500 bp (a)	300 bp (b)	Amount	Genetic Background	Mutant Allele(s)	Sex	Note
Thyr-TRB^+/+	P m 2	TS28: thyroid gland	Present	Absent	Not Specified; total RNA	involves: 129 * C57BL/6		Male
Thyr-TRB^+/+	P m 2	TS28: thyroid gland	Present	Absent	Not Specified; total RNA	involves: 129 * C57BL/6		Female
Thyr-TRB^+/-	P m 2	TS28: thyroid gland	Present	Present	Not Specified; total RNA	involves: 129/Sv * C57BL/6	Thrb^tm1Mkni/Thrb⁺, Hprt1^{tm1(TG-cre)1Sasr}/Y	Male	Conditional mutant.
Thyr-TRB^+/-	P m 2	TS28: thyroid gland	Present	Present	Not Specified; total RNA	involves: 129 * C57BL/6	Thrb^tm1Mkni/Thrb⁺, Hprt1^{tm1(TG-cre)1Sasr}/Hprt1^{tm1(TG-cre)1Sasr}	Female	Conditional mutant.
Thyr-TRB^-/-	P m 2	TS28: thyroid gland	Absent (c)	Present	Not Specified; total RNA	involves: 129/Sv * C57BL/6	Thrb^tm1Mkni/Thrb^tm1Mkni, Hprt1^{tm1(TG-cre)1Sasr}/Y	Male	Conditional mutant.
Thyr-TRB^-/-	P m 2	TS28: thyroid gland	Absent (c)	Present	Not Specified; total RNA	involves: 129 * C57BL/6	Thrb^tm1Mkni/Thrb^tm1Mkni, Hprt1^{tm1(TG-cre)1Sasr}/Hprt1^{tm1(TG-cre)1Sasr}	Female	Conditional mutant.

Notes:
(a) This band corresponds to the full-length mRNA.
(b) This band corresponds to the mRNA in which exon 5 has been deleted.
(c) The full-length mRNA was either absent or barely detectable.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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