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Gene Expression Data
Assay Details
Assay
Reference: J:88490 Beigneux AP, et al., ATP-citrate lyase deficiency in the mouse. J Biol Chem. 2004 Mar 5;279(10):9557-64
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6111908
Gene symbol: Acly
Gene name: ATP citrate lyase
Reporter: lacZ
Direct Detection
Results
Specimen 2B: embryonic day 8.5; AclyGt(NPX098)Byg/Acly+ (more )
Structure Level Pattern Image Note
TS13: neural tube Strong 2B
Specimen 6B: postnatal week 4; AclyGt(NPX098)Byg/Acly+ (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Very strong 6B
TS28: Sertoli cell Sertoli cell Present 6B
Specimen 6C: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Structure Level Pattern Image Note
TS28: renal tubule Strong 6C
Specimen 6D: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Structure Level Pattern Image Note
TS28: liver Present Regionally restricted 6D Expression is in periportal hepatocytes.
Specimen 7A: embryonic day 15.0; AclyGt(NPX098)Byg/Acly+ (more )
Structure Level Pattern Image Note
TS23: brain Very strong 7A
Specimen 7B: postnatal day 1; AclyGt(NPX098)Byg/Acly+ (more )
Structure Level Pattern Image Note
TS27: brain Very strong 7B
Specimen 7C: postnatal week 3; AclyGt(NPX098)Byg/Acly+ (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Present 7C
TS28: hippocampus Present 7C
TS28: medulla oblongata Present 7C
TS28: thalamus Present 7C
Specimen 7D: postnatal month 6; AclyGt(NPX098)Byg/Acly+ (more )
Structure Level Pattern Image Note
TS28: facial nucleus Very strong 7D
TS28: cerebellum granule cell layer Present 7D
TS28: hippocampus Present 7D
TS28: medulla oblongata Present 7D
TS28: pons Present 7D
TS28: cerebellum Present Regionally restricted 7D
Specimen 8A: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Note: Double labeled: blue - Acly reporter; brown - Gfap (assay MGI:6111910).
Structure Level Pattern Image Note
TS28: thalamus Present Regionally restricted 8A Expression is in glial cells.
Specimen 8B: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Note: Double labeled with neuronal nuclei (brown).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 8B Expression is in neurons.
Specimen 8C: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Structure Level Pattern Image Note
TS28: spinal cord ventral horn Very strong 8C
Specimen 9A: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 9A
Specimen 9C: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Note: Double labeled: blue - Acly reporter; brown - Slc18a3 (assay MGI:6115017).
Structure Level Pattern Image Note
TS28: hippocampus Present 9C
Specimen 9D: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Note: Double labeled: blue - Acly reporter; brown - Rbfox3 (assay MGI:6115019).
Structure Level Pattern Image Note
TS28: pons Present Regionally restricted 9D Expression is in the nuclei.
Specimen 9E: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Note: DoubDouble labeled: blue - Acly reporter; brown - Slc18a3 (assay MGI:6115017).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 9E
Specimen 9F: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Note: Double labeled: blue - Acly reporter; brown - Chat (assay MGI:6111916).
Structure Level Pattern Image Note
TS28: deep cerebellar nucleus Present 9F
Specimen 9G: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Note: Double labeled: blue - Acly reporter; brown - Rbfox3 (assay MGI:6115019).
Structure Level Pattern Image Note
TS28: facial nucleus Present 9G
Specimen 9H: postnatal adult; AclyGt(NPX098)Byg/Acly+ (more )
Note: Double labeled: blue - Acly reporter; brown - Slc18a3 (assay MGI:6115017).
Structure Level Pattern Image Note
TS28: facial nucleus Present 9H
Specimen not shown P W 7: postnatal week 7; AclyGt(NPX098)Byg/Acly+ (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Very strong
TS28: Sertoli cell Sertoli cell Present
Specimen not shown P W 36: postnatal week 36; AclyGt(NPX098)Byg/Acly+ (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Very strong
TS28: Sertoli cell Sertoli cell Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory