Nr3c1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:245622 Madon-Simon M, et al., Defective glucocorticoid receptor signaling and keratinocyte-autonomous defects contribute to skin phenotype of mouse embryos lacking the Hsp90 co-chaperone p23. PLoS One. 2017;12(6):e0180035
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6094213
Gene symbol:	Nr3c1
Gene name:	nuclear receptor subfamily 3, group C, member 1

Antibody:	GR antibody (M-20; sc-1004)
Detection system:	Secondary antibody
Assay notes:	The authors did not specify which antibody was used, GR antibody (H-300) (MGI:6094202) could also have been used.

Results

Specimen 2a WT left: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: epidermis	Present	Regionally restricted	2a GR WT left	Expression is in basal keratinocytes, with a few positive cells in the suprabasal layers.
TS26: dermis	Present		2a GR WT left

Specimen 2a WT right: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: epidermis	Present	Regionally restricted	2a GR WT right	Expression is in basal keratinocytes, with a few positive cells in the suprabasal layers.
TS26: dermis	Present		2a GR WT right

Specimen 2a p23-/- left: embryonic day 18.5; Ptges3^{Gt(W069F07)Wrst}/Ptges3^{Gt(W069F07)Wrst} (more

)

Structure	Level	Pattern	Image	Note
TS26: back skin	Present	Regionally restricted	2a GR p23-/- left	Expression is slightly weaker compared to wild-type in some skin sections.
TS26: dermis	Present		2a GR p23-/- left	Expression is slightly weaker compared to wild-type in some skin sections.

Specimen 2a p23-/- right: embryonic day 18.5; Ptges3^{Gt(W069F07)Wrst}/Ptges3^{Gt(W069F07)Wrst} (more

)

Structure	Level	Pattern	Image	Note
TS26: epidermis	Present	Regionally restricted	2a GR p23-/- right	Expression is slightly weaker compared to wild-type in some skin sections.
TS26: dermis	Present		2a GR p23-/- right	Expression is slightly weaker compared to wild-type in some skin sections.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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