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Gene Expression Data
Assay Details
Assay
Reference: J:241329 Vanderperre B, et al., Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet. PLoS Genet. 2016 May;12(5):e1006056
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5909408
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen S4A +/+: embryonic day 13.5 (more )
Note: Triple labeled: green - Casp3; red - Tubb3 (assay MGI:5909413); blue - DAPI.
Structure Level Pattern Image Note
TS21: pons Present S4A Active Caspase 3 +/+
Specimen S4A gt/gt: embryonic day 13.5; Mpc1Gt(OST39041)Lex/Mpc1Gt(OST39041)Lex (more )
Note: Triple labeled: green - Casp3; red - Tubb3 (assay MGI:5909413); blue - DAPI.
Structure Level Pattern Image Note
TS21: pons Present S4A Active Caspase 3 gt/gt Authors report no increase in the number of apoptotic cells.
Specimen S4B +/+: embryonic day 13.5 (more )
Note: Triple labeled: green - Casp3; red - Tubb3 (assay MGI:5909413); blue - DAPI.
Structure Level Pattern Image Note
TS21: pons Present S4B merge +/+ , S4B Active Caspase 3 +/+
Specimen S4B gt/gt: embryonic day 13.5; Mpc1Gt(OST39041)Lex/Mpc1Gt(OST39041)Lex (more )
Note: Triple labeled: green - Casp3; red - Tubb3 (assay MGI:5909413); blue - DAPI.
Structure Level Pattern Image Note
TS21: pons Present S4B Active Caspage 3 gt/gt , S4B merge gt/gt Authors report no increase in the number of apoptotic cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory