Mpc1^{Gt(OST39041)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Mpc1^{Gt(OST39041)Lex}
• Name: mitochondrial pyruvate carrier 1; gene trap OST39041, Lexicon Genetics
• MGI ID: MGI:4156120
• Synonyms: MPC1^gt
• Gene: Mpc1 Location: Chr17:8502590-8516499 bp, + strand Genetic Position: Chr17, 4.92 cM
• Alliance: Mpc1^{Gt(OST39041)Lex} page

Mutation origin

• Mutant Cell Line: OST39041
• Germline Transmission: Earliest citation of germline transmission: J:241329
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap inserted in the intron downstream of the ATG-containing exon. Western blot analysis confirmed the absence of protein expression in E13.5 embryos. (J:241329)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST39041	CG498039 ; (MGI Seq Detail)	3' RACE	multiple
  * GRCm39; (strand of gene trap mutagenesis)

Expression

In Mice Carrying this Mutation:

14 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mpc1 Mutation: 16 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)