Nkx3-1 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:201123 Kruithof-de Julio M, et al., Canonical Wnt signaling regulates Nkx3.1 expression and luminal epithelial differentiation during prostate organogenesis. Dev Dyn. 2013 Oct;242(10):1160-71
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:5903034
Gene symbol:	Nkx3-1
Gene name:	NK3 homeobox 1

Reporter:	lacZ
	Direct Detection

Results

1D ©

Specimen 1D: embryonic day 17.5; Nkx3-1^tm2Mms/Nkx3-1⁺ (more

)

Structure	Level	Image
TS25: prostate epithelium	Present	1D
TS25: bladder	Absent	1D
TS25: seminal vesicle	Absent	1D
TS25: testis	Absent	1D

1E ©

1F ©

Specimen 1E: postnatal day 1; Nkx3-1^tm2Mms/Nkx3-1⁺ (more

)
Note: (F) is a higher magnification of (E).

Structure	Level	Image
TS27: prostate epithelium	Present	1F , 1E
TS27: bladder	Absent	1E
TS27: seminal vesicle	Absent	1E
TS27: testis	Absent	1E

1G ©

Specimen 1G: postnatal day 4; Nkx3-1^tm2Mms/Nkx3-1⁺ (more

)

Structure	Level	Image
TS28: dorsal prostatic epithelium	Present	1G
TS28: lateral prostatic epithelium	Present	1G
TS28: ventral prostatic epithelium	Present	1G
TS28: seminal vesicle	Absent	1G

1H ©

Specimen 1H: postnatal day 4; Nkx3-1^tm2Mms/Nkx3-1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: anterior prostatic epithelium	Present		1H
TS28: dorsal prostatic epithelium	Present		1H
TS28: lateral prostatic epithelium	Present		1H
TS28: prostate duct	Strong	Regionally restricted	1H	Expression is highest at the distal ends.
TS28: seminal vesicle	Absent		1H

1I ©

Specimen 1I: postnatal day 4; Nkx3-1^tm2Mms/Nkx3-1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: anterior prostatic epithelium	Present		1I
TS28: dorsal prostatic epithelium	Present		1I
TS28: prostate duct	Present	Regionally restricted	1I	Expression is highest at the distal ends.
TS28: seminal vesicle	Absent		1I

1J ©

Specimen 1J: postnatal day 8; Nkx3-1^tm2Mms/Nkx3-1⁺ (more

)

Structure	Level	Image
TS28: anterior prostatic epithelium	Present	1J
TS28: lateral prostatic epithelium	Present	1J
TS28: ventral prostatic epithelium	Present	1J
TS28: seminal vesicle	Absent	1J

1K ©

Specimen 1K: postnatal day 12; Nkx3-1^tm2Mms/Nkx3-1⁺ (more

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Structure	Level	Image
TS28: anterior prostatic epithelium	Present	1K
TS28: dorsal prostatic epithelium	Present	1K
TS28: seminal vesicle	Absent	1K

1L ©

Specimen 1L: postnatal day 12; Nkx3-1^tm2Mms/Nkx3-1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: prostate epithelium	Present		1L
TS28: peri-prostatic mesenchyme	Absent		1L

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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