Nkx3-1^tm2Mms
Targeted Allele Detail

Summary

• Symbol: Nkx3-1^tm2Mms
• Name: NK3 homeobox 1; targeted mutation 2, Michael M Shen
• MGI ID: MGI:3038373
• Synonyms: Nkx3.1^tm2(lacZ)Mms
• Gene: Nkx3-1 Location: Chr14:69428141-69432107 bp, + strand Genetic Position: Chr14, 36.02 cM
• Alliance: Nkx3-1^tm2Mms page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:88802
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The endogenous gene was disrupted by the insertion of cassette containing lacZ. Beta-galactosidase was expressed from this allele. (J:88802)

Expression

In Mice Carrying this Mutation:

30 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nkx3-1 Mutation: 39 strains or lines available

References

• Original: J:88802 Berman DM, et al., Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis. Dev Biol. 2004 Mar 15;267(2):387-98
• All: 4 reference(s)