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Gene Expression Data
Assay Details
Assay
Reference: J:73810 Niederreither K, et al., Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse. Mech Dev. 2002 Jan;110(1-2):165-71
Assay type: RNA in situ
MGI Accession ID: MGI:5829765
Gene symbol: Aldh1a3
Gene name: aldehyde dehydrogenase family 1, subfamily A3
Probe: Raldh3 cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen E12.5 not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: main bronchus epithelium Weak
TS20: olfactory epithelium Present Regionally restricted Expression in part of the olfactory epithelium.
TS20: nasal mesenchyme Present Regionally restricted Expression in mesenchymal cells underlying the nasal turbinates.
TS20: skeletal muscle Weak Authors report low level of expression in developing muscles.

Specimen 1C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: main bronchus epithelium Weak 1C
TS22: olfactory epithelium Present Regionally restricted 1C Expression in part of the olfactory epithelium.
TS22: nasal mesenchyme Present Regionally restricted 1C Expression in mesenchymal cells underlying the nasal turbinates.
TS22: skeletal muscle Weak 1C Authors report low level of expression in developing muscles.

Specimen 1F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: genitourinary system epithelium Strong Regionally restricted 1F
TS22: tongue muscle Present 1F

Specimen E15.5 not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: skeletal muscle Present Authors report expression in other developing muscles.

Specimen 2D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: metanephros Present Regionally restricted 2D
TS24: liver Absent 2D

Specimen 2D inset: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: collecting duct Present 2D inset

Specimen 2H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: small intestine lamina propria Present 2H
TS24: large intestine lamina propria Absent 2H

Specimen 2K: postnatal day 22 (more )
Structure Level Pattern Image Note
TS28: papillary duct Present 2K Expression persisted in the collecting duct of the renal papilla.
TS28: renal medulla Present 2K

Specimen 2K inset: postnatal day 22 (more )
Structure Level Pattern Image Note
TS28: adrenal medulla Present 2K inset

Specimen 2P: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: male reproductive system epithelium Present Regionally restricted 2P Expression restricted to part of the genital epithelia, likely to be the developing coagulating glands and/or seminal vesicles.

Specimen 4D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: nasal epithelium Ambiguous 4D Authors report epithelial expression mostly downregulated by E16.5.
TS24: vomeronasal organ mesenchyme Absent 4D

Specimen 4H: postnatal day 22 (more )
Structure Level Pattern Image Note
TS28: nose Ambiguous 4H

Specimen 5D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: neural retina Present 5D
TS24: telencephalon Present Regionally restricted 5D Expression in cells extending along each side of the lateral ventricle septal fork, especially towards the striatum.

Specimen 5K: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dental sac Present Regionally restricted 5K
TS24: upper jaw molar mesenchyme Present Regionally restricted 5K
TS24: tooth epithelium Present Regionally restricted 5K Expression in epithelial loop separting the inner and outer dental epithelium.

Specimen 5L: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dental sac Present Regionally restricted 5L
TS24: lower jaw incisor mesenchyme Present Regionally restricted 5L
TS24: tooth epithelium Present Regionally restricted 5L Expression in epithelial loop separting the inner and outer dental epithelium.

Specimen 5P: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: upper jaw incisor dental papilla Present Regionally restricted 5P Expression in central areas of the incisor papilla mesenchyme.

Specimen postnatal day 5 not shown: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: eye Present Regionally restricted Expression at the retina/iris junction.
TS28: molar dental papilla Absent
TS28: hair inner root sheath Present Expression at the base of hair follicles, most likely in the inner epidermal root sheath.

Specimen 6D: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 6D Specific expression in the superficial layer of the posterior cerebral cortex.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory