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Gene Expression Data
Assay Details
Assay
Reference: J:152922 Golson ML, et al., Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5827902
Gene symbol: Gcg
Gene name: glucagon
Antibody: anti-Glucagon
Detection system: Cy3
Results
Specimen 1G/J: embryonic day 14.5 (more )
Note: Triple labeled: red - Gluc (Gcg); green - Jag1 (assay MGI:5827901); blue - DAPI.
Structure Level Pattern Image Note
TS22: pancreas parenchyma Present Regionally restricted 1J , 1G Expression in differentiated alpha cells.
Specimen E16.5 not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: endocrine pancreas Present Regionally restricted Expression in differentiated endocrine cells.
Specimen 3A: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo (more )
Note: Authors state that littermate Jag1loxP/loxP and Jag1loxP/+ mice were used as controls in most experiments. Double labeled: red - Gluc (Gcg); green - Ins1 (assay MGI:5827906) and Ins2 (assay MGI:5827907).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Present Regionally restricted 3A
Specimen 3B: postnatal day 21; Jag1tm1.1Loo/Jag1tm1.1Loo, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Double labeled: red - Gluc (Gcg); green - Ins1 (assay MGI:5827906) and Ins2 (assay MGI:5827907).
Structure Level Pattern Image Note
TS28: pancreas parenchyma Present Regionally restricted 3B Authors report an approximate 2.5-fold increase in alpha-cell mass by P21 in mutants vs. controls.
Specimen 6E: embryonic day 16.5; Jag1tm1.1Loo/Jag1tm1.1Loo (more )
Note: Authors state that littermate Jag1loxP/loxP and Jag1loxP/+ mice were used as controls in most experiments. Double labeled: red - Gluc (Gcg); green - Ins1 (assay MGI:5827906) and Ins2 (assay MGI:5827907).
Structure Level Pattern Image Note
TS24: pancreas parenchyma Present Regionally restricted 6E
Specimen 6F: embryonic day 16.5; Jag1tm1.1Loo/Jag1tm1.1Loo, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant. Double labeled: red - Gluc (Gcg); green - Ins1 (assay MGI:5827906) and Ins2 (assay MGI:5827907).
Structure Level Pattern Image Note
TS24: pancreas parenchyma Present Regionally restricted 6F Authors report that the number of expressing cells was reduced by approximately one-half.
Specimen E18.5 Control not shown: embryonic day 18.5; Jag1tm1.1Loo/Jag1tm1.1Loo (more )
Note: Authors state that littermate Jag1loxP/loxP and Jag1loxP/+ mice were used as controls in most experiments.
Structure Level Pattern Image Note
TS26: pancreas Present
Specimen E18.5 Mutant not shown: embryonic day 18.5; Jag1tm1.1Loo/Jag1tm1.1Loo, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: pancreas Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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