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Gene Expression Data
Assay Details
Assay
Reference: J:69276 Davis RJ, et al., Characterization of mouse Dach2, a homologue of Drosophila dachshund. Mech Dev. 2001 Apr;102(1-2):169-79
Assay type: RNA in situ
MGI Accession ID: MGI:5818542
Gene symbol: Dach2
Gene name: dachshund family transcription factor 2
Probe: Dach2 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: future midbrain Absent 4A
TS13: future prosencephalon Absent 4A
TS13: future hindbrain Present Regionally restricted 4A Expression within hindbrain, anterior to preotic sulcus.
TS13: somite Absent 4A No expression in developing somites.

Specimen 4B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 4B Expression within ventral forebrain.
TS15: branchial arch Present 4B
TS15: future hindbrain Present 4B
TS15: head mesenchyme Present 4B
TS15: neural tube Present 4B
TS15: otic pit Present 4B
TS15: somite Present Regionally restricted 4B Authors report expression in trunk mesoderm lateral to the neural tube and in the interlimb bud region in a repeated pattern suggesting expression in somites.

Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present 4C
TS17: telencephalon Present 4C
TS17: midbrain Present Regionally restricted 4C Expression in dorsal mesencephalon.
TS17: neural tube Present Regionally restricted 4C Expression in dorsal neural tube, with highest expression near the hindbrain.
TS17: lens pit Present Regionally restricted 4C Authors report a small ring of ocular staining suggesting expression in the lens pit.
TS17: inner ear Present Regionally restricted 4C Expression in the otic endolymphatic duct.
TS17: branchial arch Present 4C
TS17: dorsal root ganglion Present 4C
TS17: head mesenchyme Present 4C
TS17: somite Present Regionally restricted 4C Expression in a repeated pattern in trunk mesoderm lateral to the neural tube and in the interlimb bud region suggesting expression in somite derivatives.
TS17: forelimb bud Present Regionally restricted 4C Expression in anterior and posterior margins and presumptive handplate of limb bud.

Specimen 4D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present 4D
TS19: telencephalon Present 4D
TS19: midbrain Present Regionally restricted 4D Expression in dorsal mesencephalon.
TS19: neural tube Present Regionally restricted 4D Expression in dorsal neural tube, with highest expression near the hindbrain.
TS19: inner ear Present Regionally restricted 4D Expression in the otic endolymphatic duct.
TS19: forelimb bud Present Regionally restricted 4D Expression in anterior and posterior margins.
TS19: handplate Present Regionally restricted 4D
TS19: somite Present Regionally restricted 4D Expression in a repeated pattern in trunk mesoderm lateral to the neural tube and in the interlimb bud region suggesting expression in somite derivatives.
TS19: cranial ganglion Present 4D
TS19: dorsal root ganglion Present 4D
TS19: eye mesenchyme Present Regionally restricted 4D Expression in mesenchyme surrounding eye.
TS19: branchial arch Present Regionally restricted 4D Expression in branchial arches, with strong expression at the cranial sinus.

Specimen 4E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present 4E
TS20: telencephalon Present 4E
TS20: midbrain Present Regionally restricted 4E Expression in dorsal mesencephalon.
TS20: spinal cord Present Regionally restricted 4E Expression in dorsal neural tube (highest expression near the hindbrain.)
TS20: retina Strong Regionally restricted 4E Expression is more pronounced in the retina.
TS20: neural retina Weak Regionally restricted 4E Low levels of expression in the peripheral neuroretina.
TS20: inner ear Present Regionally restricted 4E Expression in the otic endolymphatic duct.
TS20: forelimb Present Regionally restricted 4E Expression in the limb has become more uniform and higher in the distal edges (margins) of the limb plate.
TS20: somite Present Regionally restricted 4E Expression in a repeated pattern in trunk mesoderm lateral to the neural tube and in the interlimb bud region suggesting expression in somite derivatives.

Specimen 4F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 4F Striped expression in telencephalic vesicles.
TS20: midbrain Present Regionally restricted 4F Expression in dorsal mesencephalon.
TS20: eye Present 4F
TS20: hindbrain Present 4F

Specimen 4G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: genital tubercle Present 4G
TS22: main olfactory bulb Present 4G
TS22: vibrissa Present 4G
TS22: hand Present Regionally restricted 4G Expression in hand plate and lateral edges of digits.
TS22: mammary gland primordium Present Regionally restricted 4G Expression in mammary gland primordia on the abdomen and associated with each limb.
TS22: naris Present 4G Expression in nasal opening.

Specimen 4H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hand Present Regionally restricted 4H Expression in hand plate and lateral edges of digits.
TS22: naris Present 4H Expression in nasal opening and vibrissae.

Specimen 5A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 5A Expression within forebrain neurectoderm flanked the optic vesicle with rostral and caudal restrictions.
TS15: future midbrain Present Regionally restricted 5A Expression in dorsal and ventral domains in hindbrain.
TS15: eye mesenchyme Present Regionally restricted 5A Expression in head mesoderm associated with the developing eye.

Specimen 5B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 5B Expression in the dorsal and ventral neural tube.
TS15: branchial arch Present 5B
TS15: dorsal root ganglion Present 5B
TS15: head mesenchyme Present 5B
TS15: mesenchyme derived from lateral plate Present 5B
TS15: dermomyotome Ambiguous 5B In sections anterior to the forelimb, authors state expression in dermomyotome was not as readily detectable.
TS15: limb mesenchyme Present Regionally restricted 5B Expression within a dorsal domain within the limb bud.

Specimen 5C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 5C Expression within neuroectoderm distal to the developing optic vesicle is stronger than weak expression near the vesicle rim.
TS15: optic vesicle Absent 5C No expression within the optic vesicle or in the overying lens placode ectoderm.
TS15: eye mesenchyme Present Regionally restricted 5C Expression in mesoderm adjacent to optic vesicle.
TS15: branchial arch Present 5C
TS15: head mesenchyme Present 5C

Specimen 5D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 5D In the trunk, expression in dorsal neural tube.
TS17: dorsal root ganglion Present Regionally restricted 5D
TS17: limb mesenchyme Present Regionally restricted 5D
TS17: mesenchyme derived from lateral plate Present Regionally restricted 5D

Specimen 5E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lens pit Present Regionally restricted 5E Expression in the lens epithelium.
TS17: eye mesenchyme Present Regionally restricted 5E Expression in the mesenchyme surrounding retina.
TS17: retina Weak Regionally restricted 5E Low levels of expression in the peripheral neuroretina.
TS17: head mesenchyme Present Regionally restricted 5E Expression in head mesoderm associated with the developing eye.
TS17: branchial arch Present 5E

Specimen 5F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Present 5F
TS17: mesenchyme derived from lateral plate Present 5F

Specimen not shown Small eye homozygote: embryonic day 9.5; Pax6Sey-Neu/Pax6Sey-Neu (more )
Structure Level Pattern Image Note
TS15: embryo Present Authors report no abrogation of expression in the mutant compared to wild type embryos.

Specimen not shown Splotch homozygote: embryonic day 9.5; Pax3Sp-2H/Pax3Sp-2H (more )
Structure Level Pattern Image Note
TS15: embryo Present Authors report no abrogation of expression in the mutant compared to wild type embryos.

Specimen 6A: embryonic day 9.5; Pax6Sey-Neu/Pax6+ (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 6A Expression in forebrain at level of optic vesicle.

Specimen 6B: embryonic day 9.5; Pax6Sey-Neu/Pax6Sey-Neu (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 6B Expression in forebrain at level of optic vesicle. Authors report no detectable differences in the mutant compared to wild type embryos.

Specimen 6C: embryonic day 9.5; Pax3Sp-2H/Pax3+ (more )
Structure Level Pattern Image Note
TS15: dermomyotome Ambiguous 6C In sections anterior to the forelimb, authors state expression in dermomyotome was not as readily detectable.
TS15: trunk mesenchyme Present Regionally restricted 6C Expression in cells located along the lateral portion of the trunk.
TS15: limb bud Present Regionally restricted 6C Expression in within a dorsal domain within the limb bud.

Specimen 6D: embryonic day 9.5; Pax3Sp-2H/Pax3Sp-2H (more )
Structure Level Pattern Image Note
TS15: embryo Present 6D Authors report no gross differences in expression in the dorsal neural tube in the mutant compared to wild type embryos.

Specimen 6E: embryonic day 9.5; Pax3Sp-2H/Pax3+ (more )
Structure Level Pattern Image Note
TS15: dermomyotome Present 6E In sections at forelimb level, expression within the dermomyotome.
TS15: trunk mesenchyme Present Regionally restricted 6E Expression in cells located along the lateral portion of the trunk.
TS15: limb bud Present Regionally restricted 6E Expression in within a dorsal domain within the limb bud.

Specimen 6F: embryonic day 9.5; Pax3Sp-2H/Pax3Sp-2H (more )
Structure Level Pattern Image Note
TS15: embryo Present 6F Authors report no gross differences in expression in the dermomyotome in the mutant compared to wild type embryos.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory