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Gene Expression Data
Assay Details
Assay
Reference: J:223384 Abdelhamed ZA, et al., The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway. Dis Model Mech. 2015 Jun;8(6):527-41
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5816846
Gene symbol: Gnai3
Gene name: G protein subunit alpha i3
Antibody: Anti-G-alpha-i3 (G4040)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3B Tmem67+/-: postnatal day 0; Tmem67tm1Dgen/Tmem67+ (more )
Note: Confocal image of the basal turn. Double labeled: green - Gnai3; red - actin.
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 3B Tmem67+/- Expression was detected in the lateral 'bare zone' on the apical surface of outer hair cells.
Specimen 3B Tmem67-/-: postnatal day 0; Tmem67tm1Dgen/Tmem67tm1Dgen (more )
Note: Confocal image of the basal turn. Double labeled: green - Gnai3; red - actin.
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 3B Tmem67-/- Expression was detected in the lateral 'bare zone' on the apical surface of outer hair cells as in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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