Tmem67^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Tmem67^tm1Dgen
• Name: transmembrane protein 67; targeted mutation 1, Deltagen
• MGI ID: MGI:5292220
• Gene: Tmem67 Location: Chr4:12039355-12090020 bp, - strand Genetic Position: Chr4, 5.56 cM
• Alliance: Tmem67^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176174
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A beta-geo cassette with a 5' IRES has replaced a gene segment that includes exons 2 and 3. (J:176174)

Disease models

Expression

In Mice Carrying this Mutation:	19 assay results
In Structures Affected by this Mutation:	26 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tmem67 Mutation: 64 strains or lines available

References

• Original: J:176174 Garcia-Gonzalo FR, et al., A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition. Nat Genet. 2011 Aug;43(8):776-84
• All: 5 reference(s)