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Gene Expression Data
Assay Details
Assay
Reference: J:210059 Szenasi T, et al., Hmgb1 can facilitate activation of the matrilin-1 gene promoter by Sox9 and L-Sox5/Sox6 in early steps of chondrogenesis. Biochim Biophys Acta. 2013 Oct;1829(10):1075-91
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5816095
Gene symbol: Hmgb1
Gene name: high mobility group box 1
Antibody: Hmgb1 antibody (M137-3)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 5A: embryonic day 12.0 (more )
Note: Double labeled: red - Hmgb1; green - Sox9 (assay MGI:5816096).
Structure Level Pattern Image Note
TS20: foot mesenchyme Present Regionally restricted 5A merge , 5A Hmgb1 Expression is in condensed mesenchyme.
TS20: foot pre-cartilage condensation Present Regionally restricted 5A Hmgb1 , 5A merge Expression is in prechondrocytes and early chondroblasts.
Specimen 5B: embryonic day 14.5 (more )
Note: Double labeled: red - Hmgb1; green - Sox9 (assay MGI:5816096).
Structure Level Pattern Image Note
TS22: foot mesenchyme Present Regionally restricted 5B Hmgb1 , 5B merge Expression is in condensed mesenchyme.
TS22: foot cartilage condensation Present Regionally restricted 5B merge , 5B Hmgb1 Expression is in prechondrocytes and early chondroblasts.
Specimen 5C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: foot mesenchyme Present Regionally restricted 5C merge , 5C Hmgb1 Expression is in condensed mesenchyme.
TS22: foot cartilage condensation Present Regionally restricted 5C Hmgb1 , 5C merge Expression is in prechondrocytes and early chondroblasts.
Specimen 5D: embryonic day 14.5 (more )
Note: Double labeled: red - Hmgb1; green - Sox9 (assay MGI:5816096).
Structure Level Pattern Image Note
TS22: foot mesenchyme Present Regionally restricted 5D Hmgb1 , 5D merge Expression is in condensed mesenchyme.
TS22: foot cartilage condensation Present Regionally restricted 5D merge , 5D Hmgb1 Expression is in prechondrocytes.
TS22: metatarsus cartilage condensation Present Regionally restricted 5D Hmgb1 , 5D merge Expression is in early chondroblasts of developing metatarsals.
Specimen 5E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: foot mesenchyme Present Regionally restricted 5E merge , 5E Hmgb1 Expression is in condensed mesenchyme.
TS22: foot cartilage condensation Present Regionally restricted 5E Hmgb1 , 5E merge Expression is in prechondrocytes.
TS22: metatarsus cartilage condensation Present Regionally restricted 5E Hmgb1 , 5E merge Expression is in early chondroblasts of developing metatarsals.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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