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Gene Expression Data
Assay Details
Assay
Reference: J:233954 Tu S, et al., Co-repressor CBFA2T2 regulates pluripotency and germline development. Nature. 2016 Jun 16;534(7607):387-90
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5811256
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Y-17; sc-17320)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen ED4g +/+: embryonic day 7.25 (more )
Note: Double labeled: red - Sox2; green - Tfap2c (assay MGI:5811138). Mid-bud stage.
Structure Level Pattern Image Note
TS11: primordial germ cell Present ED4g +/+ Merged , ED4g +/+ Sox2
Specimen ED4g -/-: embryonic day 7.25; Cbfa2t2em1Dare/Cbfa2t2em1Dare (more )
Note: Double labeled: red - Sox2; green - Tfap2c (assay MGI:5811138). Mid-bud stage.
Structure Level Pattern Image Note
TS11: primordial germ cell Present ED4g -/- Merged , ED4g -/- Sox2 Sox2 was not activated in primordial germ cells in the mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory