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Gene Expression Data
Assay Details
Assay
Reference: J:104952 Pedersen JK, et al., Endodermal expression of Nkx6 genes depends differentially on Pdx1. Dev Biol. 2005 Dec 15;288(2):487-501
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5806614
Gene symbol: Nkx6-2
Gene name: NK6 homeobox 2
Reporter: lacZ
Direct Detection
Results
Specimen 7G: embryonic day 8.5; Nkx6-2tm1Ercs/Nkx6-2+ (more )
Structure Level Pattern Image Note
TS13: endoderm Present Regionally restricted 7G Early expression in two lateral regions located at the border between primitive and definitive endoderm. Domain in ventral endoderm includes ventrolateral part of definitve endoderm, as well as the visceral endoderm.
TS13: neural ectoderm Present 7G Expression in the central nervous system.

Specimen 7H: embryonic day 8.5; Nkx6-2tm1Ercs/Nkx6-2+ (more )
Structure Level Pattern Image Note
TS13: foregut-midgut junction endoderm Present Regionally restricted 7H No expression in definitive dorsal endoderm including the prospective dorsal pancreas.
TS13: future spinal cord Present 7H

Specimen 7I: embryonic day 9.5; Nkx6-2tm1Ercs/Nkx6-2+ (more )
Structure Level Pattern Image Note
TS15: pancreas primordium dorsal bud Present Regionally restricted 7I Expression in the dorsal pancreatic epithelium.
TS15: pancreas primordium ventral bud Present Regionally restricted 7I Expression in the two ventral buds.

Specimen 7J: embryonic day 9.5; Nkx6-2tm1Ercs/Nkx6-2+ (more )
Structure Level Pattern Image Note
TS15: pancreas primordium dorsal bud Present Regionally restricted 7J Expression in the dorsal pancreatic epithelium.
TS15: pancreas primordium ventral bud Present Regionally restricted 7J Expression in the two ventral buds.

Specimen 7K: embryonic day 9.5; Nkx6-2tm1Ercs/Nkx6-2+ (more )
Structure Level Pattern Image Note
TS15: foregut epithelium Present Regionally restricted 7K No expression in stomach epithelium.

Specimen 7L: embryonic day 10.5; Nkx6-2tm1Ercs/Nkx6-2+ (more )
Structure Level Pattern Image Note
TS17: pancreas primordium dorsal bud Present Regionally restricted 7L Expression in dorsal and ventral pancreatic epithelium.
TS17: pancreas primordium ventral bud Present Regionally restricted 7L Expression in dorsal and ventral pancreatic epithelium.
TS17: stomach Present Regionally restricted 7L Expression in posterior part of the stomach.
TS17: duodenum Present Regionally restricted 7L Expression in duodenal endoderm.

Specimen 7M: embryonic day 10.5; Nkx6-2tm1Ercs/Nkx6-2+ (more )
Structure Level Pattern Image Note
TS17: pancreas primordium dorsal bud Present Regionally restricted 7M Expression in dorsal and ventral pancreatic epithelium.
TS17: pancreas primordium ventral bud Present Regionally restricted 7M Expression in dorsal and ventral pancreatic epithelium.
TS17: duodenum Present Regionally restricted 7M Expression in duodenal endoderm.

Specimen 7N: embryonic day 10.5; Nkx6-2tm1Ercs/Nkx6-2+ (more )
Structure Level Pattern Image Note
TS17: stomach Present Regionally restricted 7N Expression in posterior part of the stomach.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory