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Gene Expression Data
Assay Details
Assay
Reference: J:97216 Weninger WJ, et al., Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development. Development. 2005 Mar;132(6):1337-48
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5789126
Gene symbol: Cited2
Gene name: Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 7.5; Cited2tm1Jpmb/Cited2+ (more )
Note: Late headfold stage embryo.
Structure Level Pattern Image Note
TS11: node Present Regionally restricted 1A Expression is in the ventral node, predominantly in the caudal lip and pit.
TS11: blood island Present 1A
TS11: cardiogenic plate Present 1A
Specimen 1B: embryonic day 8.0; Cited2tm1Jpmb/Cited2+ (more )
Note: Flatmount of a 4 somite stage embryo.
Structure Level Pattern Image Note
TS12: cardiogenic plate Present 1B
TS12: node Present Regionally restricted 1B Expression is in the caudal lip and pit.
Specimen 1G: embryonic day 9.5; Cited2tm1Jpmb/Cited2+ (more )
Note: 21 somite stage embryo.
Structure Level Pattern Image Note
TS15: future forebrain Strong Regionally restricted 1G Expression is at the forebrain midbrain boundary.
TS15: future midbrain Strong Regionally restricted 1G Expression is at the forebrain midbrain boundary.
TS15: 1st branchial arch Strong 1G
TS15: 2nd branchial arch Strong 1G
TS15: 3rd branchial arch Strong 1G
TS15: heart Strong 1G
TS15: somite Strong 1G
Specimen 1H: embryonic day 9.5; Cited2tm1Jpmb/Cited2+ (more )
Note: 21 somite stage embryo.
Structure Level Pattern Image Note
TS15: rhombomere 3 Present 1H
TS15: rhombomere 5 Present 1H
TS15: rhombomere 6 Present 1H
TS15: rhombomere 7 Present 1H
TS15: paraxial mesenchyme Present Regionally restricted 1H Expression is adjacent to the hindbrain expression sites.
TS15: neural ectoderm Present Regionally restricted 1H Expression is in the dorsal neuroectoderm.
Specimen 1I: embryonic day 9.5; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Note: 21 somite stage embryo.
Structure Level Pattern Image Note
TS15: primitive ventricle cardiac muscle Present 1I
TS15: outflow tract Present Regionally restricted 1I Expression is in the trabeculae.
TS15: primitive ventricle Present Regionally restricted 1I Expression is in the right ventricle.
Specimen 1J: embryonic day 9.5; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Note: 1 somite stage embryo.
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 1J Including the myocardium adjacent to the endocardial cushions of the outflow tract and the atrioventricular canal.
TS15: atrioventricular endocardial cushion Weak 1J
TS15: endocardial lining Weak 1J
TS15: outflow tract endocardial cushion Weak 1J
Specimen 1K: embryonic day 9.5; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Note: 1 somite stage embryo.
Structure Level Pattern Image Note
TS15: aortic sac Present 1K
TS15: heart atrium Present 1K
TS15: sinus venosus Present 1K
Specimen 1L: embryonic day 10.5; Cited2tm1Jpmb/Cited2+ (more )
Structure Level Pattern Image Note
TS17: 4th branchial arch Present 1L
TS17: atrioventricular canal Present 1L
TS17: central nervous system Present 1L
TS17: limb Present 1L
TS17: outflow tract Present 1L
TS17: somite Present 1L
Specimen 1M: embryonic day 10.5; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Structure Level Pattern Image Note
TS17: outflow tract Present 1M
TS17: primitive ventricle cardiac muscle Present 1M
Specimen 1N: embryonic day 10.5; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Structure Level Pattern Image Note
TS17: cardiac muscle tissue Present Regionally restricted 1N Expression is adjacent to the endocardial cushion of the atrioventricular canal.
Specimen 1O: embryonic day 13.5; Cited2tm1Jpmb/Cited2+ (more )
Structure Level Pattern Image Note
TS21: outflow tract Present 1O
Specimen 1P: embryonic day 13.5; Cited2tm1Jpmb/Cited2+ (more )
Structure Level Pattern Image Note
TS21: heart Present 1P Expression is in the inflow region.
Specimen 1Q: embryonic day 13.5; Cited2tm1Jpmb/Cited2tm1Jpmb (more )
Structure Level Pattern Image Note
TS21: atrioventricular endocardial cushion Present 1Q
TS21: septum primum Present 1Q
TS21: vena cava Present 1Q
TS21: interventricular septum Present Regionally restricted 1Q Expression is at the tip.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory