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Gene Expression Data
Assay Details
Assay
Reference: J:133600 Aoki M, et al., R-spondin2 expression in the apical ectodermal ridge is essential for outgrowth and patterning in mouse limb development. Dev Growth Differ. 2008 Feb;50(2):85-95
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5788472
Gene symbol: Rspo2
Gene name: R-spondin 2
Reporter: lacZ
Direct Detection
Results
Specimen 2C: embryonic day 9.5; Rspo2tm1Hoka/Rspo2+ (more )
Structure Level Pattern Image Note
TS15: diencephalon Present Regionally restricted 2C Expression in dorsal telencephalon and dorsal diencephalon.
TS15: telencephalon Present Regionally restricted 2C Expression in dorsal telencephalon and dorsal diencephalon.
TS15: branchial arch Present Regionally restricted 2C Expression limited more posteriorly compared with Rspo2 mRNA expression (see assay MGI:5788473).
Specimen 2D: embryonic day 10.5; Rspo2tm1Hoka/Rspo2+ (more )
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 2D Expression in dorsal telencephalon and dorsal diencephalon.
TS17: telencephalon Present Regionally restricted 2D Expression in dorsal telencephalon and dorsal diencephalon.
TS17: brain Present Regionally restricted 2D Expression in dorsal midline of brain.
TS17: branchial arch Present Regionally restricted 2D Expression limited more posteriorly compared with Rspo2 mRNA expression (see assay MGI:5788473).
TS17: apical ectodermal ridge Present 2D
Specimen 2E: embryonic day 10.5; Rspo2tm1Hoka/Rspo2+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present 2E
TS17: forelimb bud Present Regionally restricted 2E Authors report expression in a ventral proximal region.
Specimen 2F: embryonic day 10.5; Rspo2tm1Hoka/Rspo2+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present 2F
TS17: hindlimb bud Present Regionally restricted 2F Authors report expression in a ventral proximal region.
Specimen 2G: embryonic day 11.5; Rspo2tm1Hoka/Rspo2+ (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 2G
TS19: handplate apical ectodermal ridge Present 2G
Specimen 2H: embryonic day 13.5; Rspo2tm1Hoka/Rspo2+ (more )
Structure Level Pattern Image Note
TS21: foot epithelium Present Regionally restricted 2H Authors report expression in the apical ectodermal ridge.
TS21: hand epithelium Present Regionally restricted 2H Authors report expression in the apical ectodermal ridge.
Specimen 2I: embryonic day 13.5; Rspo2tm1Hoka/Rspo2+ (more )
Structure Level Pattern Image Note
TS21: hand epithelium Present Regionally restricted 2I Authors report expression in the apical ectodermal ridge.
Specimen 2J: embryonic day 13.5; Rspo2tm1Hoka/Rspo2+ (more )
Structure Level Pattern Image Note
TS21: foot epithelium Present Regionally restricted 2J Authors report expression in the apical ectodermal ridge.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory