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Gene Expression Data
Assay Details
Assay
Reference: J:3129 Dong LJ, et al., The expression of the genes for entactin, laminin A, laminin B1 and laminin B2 in murine lens morphogenesis and eye development. Differentiation. 1991 Dec;48(3):157-72
Assay type: RNA in situ
MGI Accession ID: MGI:5775012
Gene symbol: Lamb1
Gene name: laminin B1
Probe: p51
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3B: embryonic day 9.5 (more )
Note: 25 somites.
Structure Level Pattern Image Note
TS15: lens placode Present 3B

Specimen 5Aa: embryonic day 9.5-10.0 (more )
Note: 25 somites.
Structure Level Pattern Image Note
TS15: lens placode Present 5Aa
TS15: optic vesicle Present 5Aa

Specimen 5Bb: embryonic day 10.5 (more )
Note: 34 somites.
Structure Level Pattern Image Note
TS16: lens pit Present 5Bb There was a marked increase in the level of message as the lens pit formed.
TS16: optic cup outer layer Present 5Bb

Specimen 5Cc: embryonic day 10.5-11.0 (more )
Note: 38 somites.
Structure Level Pattern Image Note
TS17: lens pit Present 5Cc

Specimen 5Dd: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lens Present Regionally restricted 5Dd As the lens developed, message became localized primarily to the equator and cells at the periphery of the anterior hemisphere.
TS23: cornea epithelium Present 5Dd

Specimen 6B: embryonic day 10.5-11.0 (more )
Note: 38 somites.
Structure Level Pattern Image Note
TS17: eye mesenchyme Trace 6B
TS17: optic cup outer layer Trace 6B

Specimen 7Aa: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: vitreous humour Strong Regionally restricted 7Aa Punctate groups of cells on the vitreous aspect of the retina and closely apposed to the limiting membrane were heavily labeled with the probe. These cells are most likely hyalocytes.
TS26: lens equatorial epithelium Strong 7Aa
TS26: retina layer Present Regionally restricted 7Aa Expression was detected in the ganglion cell layer.

Specimen 7Bb: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: vitreous humour Strong Regionally restricted 7Bb Punctate groups of cells on the vitreous aspect of the retina and closely apposed to the limiting membrane were heavily labeled with the probe. These cells are most likely hyalocytes.
TS27: lens equatorial epithelium Strong 7Bb
TS27: retina ganglion cell layer Present 7Bb

Specimen 7Cc: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: vitreous humour Strong Regionally restricted 7Cc Punctate groups of cells on the vitreous aspect of the retina and closely apposed to the limiting membrane were heavily labeled with the probe. These cells are most likely hyalocytes.
TS28: lens equatorial epithelium Strong 7Cc
TS28: retina ganglion cell layer Present 7Cc
TS28: retina inner nuclear layer Present 7Cc A small number of cells were labeled.
TS28: retina inner plexiform layer Present 7Cc A small number of cells were labeled.
TS28: photoreceptor layer Absent 7Cc

Specimen 8B: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Present 8B
TS27: vitreous humour Present 8B Expression was detected in hyalocytes.
TS27: retina nuclear layer Present 8B Expression was detected in specific cells in the neuroblast layer.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory