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Gene Expression Data
Assay Details
Assay
Reference: J:218174 Hasan MZ, et al., Abnormal development of placenta in HtrA1-deficient mice. Dev Biol. 2015 Jan 1;397(1):89-102
Assay type: RNA in situ
MGI Accession ID: MGI:5751310
Gene symbol: Tpbpa
Gene name: trophoblast specific protein alpha
Probe: Tpbpa cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3E: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: ectoplacental cone Present 3I , 3E
Specimen 3L: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Regionally restricted 3-U , 3-L Expression was in the trophoblast cell lineage in the junctional zone.
Specimen 4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present 4A , 4C
Specimen 4B: embryonic day 10.5; Htra1tm1Ybf/Htra1tm1Ybf (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present 4D , 4B There were fewer expressing cells in the mutant.
Specimen 4E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spongiotrophoblast Present 4E , 4G
TS20: trophectoderm Present Regionally restricted 4G , 4E Expression was detected in glycogen trophoblast cells.
Specimen 4F: embryonic day 12.5; Htra1tm1Ybf/Htra1tm1Ybf (more )
Structure Level Pattern Image Note
TS20: spongiotrophoblast Present 4F , 4H There were fewer expressing cells in the mutant.
TS20: trophectoderm Present 4F , 4H There were fewer expressing cells in the mutant.
Specimen 4I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: spongiotrophoblast Present 4K , 4I
TS22: trophectoderm Present Regionally restricted 4I , 4K Expression was detected in glycogen trophoblast cells.
Specimen 4J: embryonic day 14.5; Htra1tm1Ybf/Htra1tm1Ybf (more )
Structure Level Pattern Image Note
TS22: spongiotrophoblast Present 4L , 4J There were fewer expressing cells in the mutant.
TS22: trophectoderm Present 4L , 4J There were fewer expressing cells in the mutant.
Specimen 5E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present 5E , 5F Expression was detected in invading spiral artery-associated trophoblast giant cells (SpA-TGCs) and some vessel-associated SpA-TGCs.
TS28: decidua Present 5E , 5F Expression was detected in invading spiral artery-associated trophoblast giant cells (SpA-TGCs) and some vessel-associated SpA-TGCs.
Specimen 5G: embryonic day 9.5; Htra1tm1Ybf/Htra1tm1Ybf (more )
Structure Level Pattern Image Note
TS15: trophoblast giant cell Present 5H , 5G Fewer expressing cells invaded the decidua and associated with maternal arteries in the mutant placentas.
TS28: decidua Present 5H , 5G Fewer expressing cells invaded the decidua and associated with maternal arteries in the mutant placentas.
Specimen S6D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spongiotrophoblast Present S6D
Specimen S6F: embryonic day 12.5; Htra1tm1Ybf/Htra1+ (more )
Structure Level Pattern Image Note
TS20: spongiotrophoblast Present S6F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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