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Gene Expression Data
Assay Details
Assay
Reference: J:152650 Ivey KN, et al., Transcriptional regulation during development of the ductus arteriosus. Circ Res. 2008 Aug 15;103(4):388-95
Assay type: RNA in situ
MGI Accession ID: MGI:5708367
Gene symbol: Epas1
Gene name: endothelial PAS domain protein 1
Probe: Hif2a probe1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 4a: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: ductus arteriosus Present Regionally restricted 4a Authors report specific expression in ductal smooth muscle.
TS21: blood vessel endothelium Present 4a
Specimen 4b: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: ductus arteriosus Ambiguous 4b Expression in ductal smooth muscle declines around birth.
TS26: blood vessel endothelium Present 4b
Specimen 4c: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: ductus arteriosus Ambiguous 4c Expression in ductal smooth muscle declines around birth.
TS27: blood vessel endothelium Present 4c Expression maintained in vascular endothelium.
Specimen 4d: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: ductus arteriosus Ambiguous 4d Expression in ductal smooth muscle declines around birth.
TS27: blood vessel endothelium Present 4d Expression maintained in vascular endothelium.
Specimen 5c: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: ductus arteriosus Present Regionally restricted 5c
TS21: blood vessel endothelium Present 5c
Specimen 5d: embryonic day 13.5; Tfap2btm1Rbu/Tfap2btm1Rbu (more )
Structure Level Pattern Image Note
TS21: ductus arteriosus Ambiguous 5d Expression diminished in ductal smooth muscle. Lower expression in mutants compared with wild type embryos.
TS21: blood vessel endothelium Present 5d Expression not diminished in endothelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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