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Gene Expression Data
Assay Details
Assay
Reference: J:54164 Turnley AM, et al., Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system. J Neurochem. 1999 Apr;72(4):1707-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5698425
Gene symbol: Prkab1
Gene name: protein kinase, AMP-activated, beta 1 non-catalytic subunit
Results
Specimen 2G: postnatal day 23 (more )
Structure Level Pattern Image Note
TS28: hippocampus pyramidal cell layer Present Regionally restricted 2G Expression in pyramidal cell nuclei.
Specimen 3E: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Regionally restricted 3E Expression in a few cells in the granular layer.
TS28: cerebellum Purkinje cell layer Weak Regionally restricted 3E Low levels of expression in Purkinje cell nuclei.
TS28: inferior colliculus Present Regionally restricted 3E Expression in some neurons in the inferior colliculus.
Specimen 4E: postnatal day 12 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb Present Regionally restricted 4E Expression only in mitral cells and some periglomerular cells.
TS28: main olfactory bulb mitral cell layer Present Regionally restricted 4E
TS28: main olfactory bulb granule cell layer Absent 4E No expression in granule cells.
Specimen 5C: postnatal day 23 (more )
Structure Level Pattern Image Note
TS28: spinal cord Present Regionally restricted 5C High expression in nucleus of motor neurons, and in some astrocytes, but not in interneurons.
Specimen Table 1: postnatal (more )
Structure Level Pattern Image Note
TS28: cerebellum white matter Ambiguous Not detectable to high expression in neurons. No expression in astrocytes.
TS28: hippocampus Present Regionally restricted Not detectable to barely detectable expression in activated astrocytes.
TS28: hippocampus pyramidal cell layer Present Regionally restricted Low to high expression in pyramidal cells.
TS28: cerebellum Purkinje cell layer Present Regionally restricted Barely detectable to medium expression in Purkinje cells.
TS28: cerebellum granule cell layer Trace Regionally restricted Barely detectable in granule cells.
TS28: spinal cord Present Regionally restricted Barely detectable to high expression in motor neurons. Not detectable to medium expression in astrocytes.
TS28: facial nucleus Present Regionally restricted Barely detectable to high expression in motor neurons.
TS28: main olfactory bulb glomerular layer Strong Regionally restricted High expression in mitral and periglomerular cells.
TS28: main olfactory bulb mitral cell layer Strong Regionally restricted High expression in mitral and periglomerular cells.
TS28: main olfactory bulb granule cell layer Absent No expression in granule cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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