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Gene Expression Data
Assay Details
Assay
Reference: J:224530 Dietrich JE, et al., Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages. EMBO Rep. 2015 Aug;16(8):1005-21
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5697012
Gene symbol: Tmem50b
Gene name: transmembrane protein 50B
Reporter: YFP
Direct Detection
Results
Specimen 2A E1.5: embryonic day 1.5; Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: 2-4 cell stage
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Ambiguous
Specimen 2A E1.5: embryonic day 1.5; Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: 2-4 cell stage
Structure Level Pattern Image Note
TS3: 4-cell stage embryo Present Ubiquitous
Specimen 2A E2.5: embryonic day 2.5; Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: 8-16 cell stage morula
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present Ubiquitous
TS3: compacted morula Present Ubiquitous
Specimen 2A E3.5: embryonic day 3.5; Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: blastocyst stage
Structure Level Pattern Image Note
TS4: trophectoderm Present
TS4: inner cell mass Absent
Specimen 2A E4.5: embryonic day 4.5; Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: blastocyst stage
Structure Level Pattern Image Note
TS6: trophectoderm Present
TS6: embryo Absent
Specimen 2B E2.5: embryonic day 2.5; Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: 8-16 cell stage morula
Structure Level Pattern Image Note
TS3: compacted morula Present Ubiquitous 2B E2.5
Specimen 2B E3.5: embryonic day 3.5; Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: blastocyst stage
Structure Level Pattern Image Note
TS4: trophectoderm Present 2B E3.5
TS4: inner cell mass Absent 2B E3.5
Specimen 3A +/+: embryonic day 3.5; Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: Fig. 3B depicts box plots of these intensities.
Structure Level Pattern Image Note
TS4: trophectoderm Present 3A +/+
Specimen not shown +/-: embryonic day 3.5; Tead4tm1Hssk/Tead4+, Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: Fig. 3B depicts box plots of these intensities.
Structure Level Pattern Image Note
TS4: trophectoderm Present
Specimen 3A -/-: embryonic day 3.5; Tead4tm1Hssk/Tead4tm1Hssk, Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: Fig. 3B depicts box plots of these intensities.
Structure Level Pattern Image Note
TS4: trophectoderm Present 3A -/- Expression levels are reduced in the mutant.
Specimen 3C +/+: embryonic day 3.5; Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: Fig. 3D depicts box plots of these intensities.
Structure Level Pattern Image Note
TS4: trophectoderm Present 3C +/+
Specimen not shown +/-: embryonic day 3.5; Cdx2tm1Fbe/Cdx2+, Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: Fig. 3D depicts box plots of these intensities.
Structure Level Pattern Image Note
TS4: trophectoderm Present
Specimen 3C -/-: embryonic day 3.5; Cdx2tm1Fbe/Cdx2tm1Fbe, Tmem50bGt(fVET17B)Hiir/Tmem50b+ (more )
Note: Fig. 3D depicts box plots of these intensities.
Structure Level Pattern Image Note
TS4: trophectoderm Present 3C -/- Expression levels are reduced in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory