About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:182578 Kay JN, et al., MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons. Nature. 2012 Mar 22;483(7390):465-9
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5660930
Gene symbol: Megf10
Gene name: multiple EGF-like-domains 10
Reporter: lacZ
Antibody: anti-B-galactosidase (Sanes)
Results
Specimen S6a: postnatal day 14; Megf10tm1a(KOMP)Jrs/Megf10+ (more )
Note: Right image is double labeled: green - Megf10; red - Chat (assay MGI:5660818).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted S6a right , S6a left Expression was detected in starburst amacrine cells, horizontal cells, and Muller glia.
TS28: retina ganglion cell layer Present Regionally restricted S6a right , S6a left Expression was detected in starburst amacrine cells.
TS28: retina inner plexiform layer Present Regionally restricted S6a left , S6a right Expression was detected in starburst amacrine cell dendrites, which project to two sublaminae in the inner plexiform layer.
Specimen S6c: postnatal day 14; Megf10tm1a(KOMP)Jrs/Megf10+ (more )
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted S6c Expression was detected in Muller glia.
TS28: retina outer nuclear layer Present Regionally restricted S6c Radial processes of Muller glia were noted in the outer nuclear layer.
Specimen S6d: postnatal day 14; Megf10tm1a(KOMP)Jrs/Megf10tm1a(KOMP)Jrs (more )
Note: Right image is double labeled: green - Megf10; red - Chat (assay MGI:5660818).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted S6d left , S6d right Expression was detected in starburst amacrine cells, horizontal cells and Muller glia.
TS28: retina ganglion cell layer Present Regionally restricted S6d left , S6d right Expression was detected in starburst amacrine cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory