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Gene Expression Data
Assay Details
Assay
Reference: J:73292 Ridanpaa M, et al., Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures. Mech Dev. 2001 Dec;109(2):173-81
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5659463
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: vibrissa epidermal component Strong Expression is present in the epithelial cells of the germs.
TS22: hair epidermal placode Present Expression is present in coat hair placodes.

Specimen 1D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa outer root sheath Present 1D Expression is present in the outer root sheath, including the bulge.
TS24: vibrissa dermal component Present 1D Expression is present in condensing mesenchyme surrounding the whisker follicle.

Specimen 1H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa bulb Strong Non-Uniform 1H There is strong expression in the inner ring of cells of the matrix and in a small subset of cells in the dermal papilla.
TS24: vibrissa dermal papilla Strong Non-Uniform 1H There is strong expression in the inner ring of cells of the matrix and in a small subset of cells in the dermal papilla.
TS24: vibrissa root sheath matrix Strong Non-Uniform 1H There is strong expression in the inner ring of cells of the matrix and in a small subset of cells in the dermal papilla.

Specimen 2D: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: vibrissa outer root sheath Present Single cells 2D
TS28: skin gland Absent 2D No expression in the whisker ringwulst.

Specimen 2G: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: vibrissa bulb Present Punctate 2G In the bulb expression is found in the lower, proliferating part of the matrix. There is no expression in the upper matrix, nor in the dermal papilla.
TS28: vibrissa root sheath matrix Present Punctate 2G In the bulb expression is found in the lower, proliferating part of the matrix. There is no expression in the upper matrix, nor in the dermal papilla.
TS28: vibrissa dermal papilla Absent 2G

Specimen not shown: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: hair root sheath matrix Present

Specimen not shown: postnatal week 5 (more )
Structure Level Pattern Image Note
TS28: sebaceous gland Present Single cells Expression is present in some germinative basal flat sebaceous cells for hair and whisker follicles.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: preputial gland of male Strong

Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: preputial gland of male Strong

Specimen not shown: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: preputial gland of male Present Regionally restricted Expression is present in epithelial cells.

Specimen 3L: postnatal; Apctm1Rak/Apc+ (more )
Note: tail cyst
Structure Level Pattern Image Note
TS28: epidermis Present Single cells 3L Expression is present in proliferating cells in the hair follicle-derived epidermal cysts found in the mutants.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory