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Gene Expression Data
Assay Details
Assay
Reference: J:73292 Ridanpaa M, et al., Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures. Mech Dev. 2001 Dec;109(2):173-81
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5659462
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Antibody: anti-beta-catenin (#610153), clone 14
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: vibrissa epidermal component Strong 1A Expression is present in the cytoplasm and the membranes of penetrating germs.

Specimen 1B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa root sheath Present 1B
TS24: vibrissa bulb Present 1B

Specimen 1C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa outer root sheath Strong 1C Expression in the bulge and rest of outer root sheath.

Specimen 1G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa dermal papilla Strong Regionally restricted 1G Expression is in the matrix and some cells of the dermal papilla.
TS24: vibrissa root sheath matrix Strong Regionally restricted 1G Expression is in the matrix and some cells of the dermal papilla.

Specimen 2A: postnatal month 1 (more )
Structure Level Pattern Image Note
TS28: vibrissa inner root sheath Strong 2A
TS28: vibrissa outer root sheath Strong 2A
TS28: vibrissa bulb Strong 2A In the bulb strong expression is seen in the upper part of the matrix and cortex.
TS28: vibrissa root sheath matrix Strong 2A In the bulb strong expression is seen in the upper part of the matrix and cortex.

Specimen 2B: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: vibrissa inner root sheath Strong 2B
TS28: vibrissa outer root sheath Strong 2B
TS28: skin gland Present 2B Expression is present in mesenchymal cells of the developing whisker ringwulst.

Specimen 2F: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: vibrissa bulb Strong Non-Uniform 2F In the bulb strong expression is seen in the upper part of the matrix and cortex. There is also expression in the lower, proliferating part of the matrix and the dermal papilla.
TS28: vibrissa dermal papilla Strong Non-Uniform 2F In the bulb strong expression is seen in the upper part of the matrix and cortex. There is also expression in the lower, proliferating part of the matrix and the dermal papilla.
TS28: vibrissa root sheath matrix Strong Non-Uniform 2F In the bulb strong expression is seen in the upper part of the matrix and cortex. There is also expression in the lower, proliferating part of the matrix and the dermal papilla.

Specimen 3A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hair epidermal placode Strong 3A

Specimen 3B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hair follicle Strong 3B Expression is elevated in the hair germs.

Specimen not shown: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: hair root sheath matrix Present Expression is present in matrix cells around the dermal papilla.
TS28: hair cortex Present
TS28: hair follicle dermal papilla Present

Specimen 3C: postnatal month 1 (more )
Structure Level Pattern Image Note
TS28: hair cortex Present 3C
TS28: hair follicle dermal papilla Present 3C
TS28: hair root sheath matrix Strong 3C

Specimen 3D: postnatal month 1 (more )
Structure Level Pattern Image Note
TS28: hair cortex Present 3D
TS28: hair root sheath matrix Strong 3D

Specimen not shown: postnatal week 5 (more )
Structure Level Pattern Image Note
TS28: sebaceous gland Weak Expression in present in sebaceous glands of both hair and whisker follicles.

Specimen 3E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: preputial gland of male Strong 3E

Specimen 3F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: preputial gland of male Strong 3F

Specimen 3H: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: preputial gland of male Strong Regionally restricted 3H Expression in the dermal papilla and matrix of the follicle, membrane staining in the sebaceous cells, and expression in the hair.

Specimen 3J: postnatal; Apctm1Rak/Apc+ (more )
Note: tail cyst
Structure Level Pattern Image Note
TS28: epidermis Strong Regionally restricted 3J Expression is present in the matrix-like cells lining the hair follicle-derived epidermal cysts of the mutant.

Specimen 3K: postnatal; Apctm1Rak/Apc+ (more )
Note: tail cyst
Structure Level Pattern Image Note
TS28: epidermis Strong Regionally restricted 3K Expression is present in the matrix-like cells lining the hair follicle-derived epidermal cysts of the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory