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Gene Expression Data
Assay Details
Assay
Reference: J:174196 Heydeck W, et al., PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube. Dev Dyn. 2011 Aug;240(8):1938-48
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5586676
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: Isl1 antibody
Detection system: Secondary antibody coupled to Cy3
Results
Specimen S2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S2A Expression is in motor neurons.
Specimen S2B: embryonic day 10.5; Ift88tm1Rpw/Ift88tm1Rpw (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S2B There are a reduced number of expressing cells in the ventral-most region.
Specimen S2C: embryonic day 10.5; Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S2C Expression is expanded to the ventral midline in this mutant.
Specimen S2D: embryonic day 10.5; Ift88tm1Rpw/Ift88tm1Rpw, Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S2D There are a few expressing cells in the ventral-most region.
Specimen S2I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S2I Expression is in motor neurons.
Specimen S2J: embryonic day 10.5; Ift88tm1Rpw/Ift88tm1Rpw (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S2J Expression is expanded to the ventral midline.
Specimen S2K: embryonic day 10.5; Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S2K Expression is slightly expanded ventrally in this mutant.
Specimen S2L: embryonic day 10.5; Ift88tm1Rpw/Ift88tm1Rpw, Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S2L The expression domain has expanded to the ventral midline in this mutant.
Specimen S4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S4A Expression is in motor neurons.
Specimen S4B: embryonic day 10.5; Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S4B Expression is expanded to the ventral midline.
Specimen S4C: embryonic day 10.5; FuzGt(AN0439)Wtsi/FuzGt(AN0439)Wtsi (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S4C Expression is expanded to the ventral midline.
Specimen S4D: embryonic day 10.5; FuzGt(AN0439)Wtsi/FuzGt(AN0439)Wtsi, Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S4D Expression is expanded to the ventral midline.
Specimen S4I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S4I Expression is in motor neurons.
Specimen S4J: embryonic day 10.5; Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S4J Expression is expanded to the ventral midline.
Specimen S4K: embryonic day 10.5; FuzGt(AN0439)Wtsi/FuzGt(AN0439)Wtsi (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S4K Expression is expanded to the ventral midline.
Specimen S4L: embryonic day 10.5; FuzGt(AN0439)Wtsi/FuzGt(AN0439)Wtsi, Intutm1.2Aliu/Intutm1.2Aliu (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Present Regionally restricted S4L Expression is expanded to the ventral midline.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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