Fuz^{Gt(AN0439)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Fuz^{Gt(AN0439)Wtsi}
• Name: fuzzy planar cell polarity protein; gene trap AN0439, Wellcome Trust Sanger Institute
• MGI ID: MGI:4346364
• Gene: Fuz Location: Chr7:44545517-44552053 bp, + strand Genetic Position: Chr7, 28.99 cM, cytoband B2
• Alliance: Fuz^{Gt(AN0439)Wtsi} page

Mutation origin

• Mutant Cell Line: AN0439
• Germline Transmission: Earliest citation of germline transmission: J:154370
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: The 5' end of the gene trap vector is inserted into intron 3, 28 bp upstream of the beginning of exon 4. In addition a large portion of the gene (intron 4 to exon 10) cannot be amplified in homozygous mice, indicating that the gene trap insertion is accompanied by an intragenic deletion spanning 7 exons. No beta-galactosidase activity is detected in homozygous or heterozygous embryos. (J:154370)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AN0439	CL569486 ; (MGI Seq Detail)	5' RACE	Chr7:44545668-44545785 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  6 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	59 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fuz Mutation: 23 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)