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Gene Expression Data
Assay Details
Assay
Reference: J:132939 Varadkar P, et al., Notch2 is required for the proliferation of cardiac neural crest-derived smooth muscle cells. Dev Dyn. 2008 Apr;237(4):1144-52
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5585607
Gene symbol: Notch2
Gene name: notch 2
Reporter: lacZ
Direct Detection
Results
Specimen 1C: embryonic day 9.5; Notch2Gt(AG0498)Wtsi/Notch2+ (more )
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present 1C
TS15: outflow tract Present 1C
TS15: heart Absent 1C
Specimen 1D: embryonic day 10.5; Notch2Gt(AG0498)Wtsi/Notch2+ (more )
Structure Level Pattern Image Note
TS17: atrioventricular canal Present Regionally restricted 1D Expression is in the mesenchyme.
Specimen 1E: embryonic day 10.5; Notch2Gt(AG0498)Wtsi/Notch2+ (more )
Note: F: Higher magnification of the boxed region of E.
Structure Level Pattern Image Note
TS17: outflow tract Present 1F , 1E
Specimen 1G: embryonic day 12.5; Notch2Gt(AG0498)Wtsi/Notch2+ (more )
Structure Level Pattern Image Note
TS20: atrioventricular canal Present Regionally restricted 1G Expression is in the mesenchyme.
TS20: outflow tract Present 1G
Specimen 1H: embryonic day 14.5; Notch2Gt(AG0498)Wtsi/Notch2+ (more )
Structure Level Pattern Image Note
TS22: dorsal aorta Strong 1H
TS22: pulmonary artery Strong 1H
Specimen 1I: embryonic day 16.5; Notch2Gt(AG0498)Wtsi/Notch2+ (more )
Note: J: Higher magnification of the boxed region of I.
Structure Level Pattern Image Note
TS24: pulmonary valve Present 1I , 1J Expression is in the valve and is absent in endothelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory