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Gene Expression Data
Assay Details
Assay
Reference: J:111609 Anderson RM, et al., Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival. Dev Dyn. 2006 Aug 7;235(9):2507-2520
Assay type: RNA in situ
MGI Accession ID: MGI:5584004
Gene symbol: Tfap2a
Gene name: transcription factor AP-2, alpha
Probe: pB240
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1D: embryonic day 8.0 (more )
Note: 6-7 somites.
Structure Level Pattern Image Note
TS12: neural crest Present 1D Expression is at the neural/surface ectoderm boundary in neural crest cells.
TS12: neural ectoderm Present 1D Expression is at the neural/surface ectoderm boundary in neural crest cells.
TS12: surface ectoderm Present 1D Expression is at the neural/surface ectoderm boundary in neural crest cells.
Specimen 1E: embryonic day 8.0; Nogtm1Amc/Nogtm1Amc (more )
Note: 5-7 somites.
Structure Level Pattern Image Note
TS12: future hindbrain Strong Regionally restricted 1E Expression is in the dorsal region.
TS12: future midbrain Strong Regionally restricted 1E Expression is in the dorsal region.
TS12: future spinal cord neural fold Strong Regionally restricted 1E Expression is in the dorsal region.
TS12: head mesenchyme Strong Regionally restricted 1E Expression is in the dorsal region.
TS12: neural ectoderm Strong Regionally restricted 1E Expression is in the dorsal region.
Specimen 1F: embryonic day 8.0; Chrdtm1Emdr/Chrdtm1Emdr, Nogtm1Amc/Nogtm1Amc (more )
Note: 5-7 somites.
Structure Level Pattern Image Note
TS12: future hindbrain Strong Regionally restricted 1F Expression is in the dorsal region.
TS12: future midbrain Strong Regionally restricted 1F Expression is in the dorsal region.
TS12: future spinal cord neural fold Strong Regionally restricted 1F Expression is in the dorsal region.
TS12: head mesenchyme Strong Regionally restricted 1F Expression is in the dorsal region.
TS12: surface ectoderm Strong Regionally restricted 1F Expression is in the dorsal region.
Specimen 4J: embryonic day 9.5 (more )
Note: Also stained for Shh (assay MGI:5584013).
Structure Level Pattern Image Note
TS15: migrating neural crest Present 4J
TS15: neural crest Present 4J
Specimen 4K: embryonic day 9.5; Nogtm1Amc/Nogtm1Amc (more )
Note: Also stained for Shh (assay MGI:5584013).
Structure Level Pattern Image Note
TS15: neural crest Strong 4K There is an increase in neural crest cells. Large ectopic aggregations of neural crest cells are seen superficial to the dorsal neural tube.
TS15: migrating neural crest Strong 4K Expanded populations of migratory neural crest cells were spread more distantly from the dorsal neural tube.
Specimen 4L: embryonic day 9.5; Chrdtm1Emdr/Chrdtm1Emdr, Nogtm1Amc/Nogtm1Amc (more )
Note: Also stained for Shh (assay MGI:5584013).
Structure Level Pattern Image Note
TS15: migrating neural crest Strong Regionally restricted 4L There is an increase in neural crest cells. Large ectopic aggregations of neural crest cells are seen superficial to the dorsal neural tube.
TS15: neural crest Strong Regionally restricted 4L There is an increase in neural crest cells. Large ectopic aggregations of neural crest cells are seen superficial to the dorsal neural tube.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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