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Gene Expression Data
Assay Details
Assay
Reference: J:84056 Motoyama J, et al., Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification. Dev Biol. 2003 Jul 1;259(1):150-61
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5575366
Gene symbol: Ptch1
Gene name: patched 1
Reporter: lacZ
Direct Detection
Results
Specimen 3A: embryonic day 9.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3A Expression is ventral.
Specimen 3B: embryonic day 9.5; Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS15: neural tube Present Ubiquitous 3B
TS15: embryo Present 3B Expression is in most of the cells except the caudal endoderm.
TS15: embryo endoderm Present 3B Absent in the caudal endoderm.
Specimen 3C: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS15: neural tube Weak Regionally restricted 3C Expression is at the ventral midline.
Specimen 3D: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3D Expanded ventral expression in the rostral neural tube and expression disappeared in the caudal neural tube.
TS15: future brain Present 3D
Specimen 3E: embryonic day 9.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3E Expression is ventral.
Specimen 3F: embryonic day 9.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS15: neural tube Present Ubiquitous 3F
TS15: embryo Present Regionally restricted 3F Expression is in most of the cells except the caudal endoderm.
Specimen 3G: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS15: neural tube Weak Regionally restricted 3G Expression is at the ventral midline.
Specimen 3H: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS15: neural tube Weak Regionally restricted 3H Expanded ventral expression in the rostral neural tube.
Specimen 3I: embryonic day 9.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 3I Expression is ventral.
Specimen 3J: embryonic day 9.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS15: neural tube Present Ubiquitous 3J
TS15: embryo Present Regionally restricted 3J Expression is in most of the cells except the caudal endoderm.
Specimen 3K: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS15: tail neural tube Absent 3K
Specimen 3L: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS15: neural tube Trace 3L
Specimen 5A: embryonic day 10.5; Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 5A Expression is in the ventral midline.
Specimen 5B: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J, Ptch1tm1Mps/Ptch1+ (more )
Structure Level Pattern Image Note
TS17: neural tube Weak 5B
Specimen 5C: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J, Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS17: neural tube Weak 5C
Specimen 5D: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3+, Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS17: neural tube Present 5D There is a slight reduction in expression in this mutant.
Specimen 5E: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Ptch1tm1Mps/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 5E The expression domain is expanded in this mutant.
Specimen 6P: embryonic day 9.5; Ptch1tm1Mps/Ptch1+ (more )
Note: This section is at the thoracic level.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 6P Expression is ventral.
Specimen 6Q: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J, Ptch1tm1Mps/Ptch1+ (more )
Note: This section is at the thoracic level.
Structure Level Pattern Image Note
TS15: neural tube Absent 6Q
Specimen 6R: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J, Ptch1tm1Mps/Ptch1tm1Mps (more )
Note: This section is at the thoracic level.
Structure Level Pattern Image Note
TS15: neural tube Weak Regionally restricted 6R Expression is ventral.
Specimen 6S: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3+, Ptch1tm1Mps/Ptch1tm1Mps (more )
Note: This section is at the thoracic level.
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 6S Expression is ventral.
Specimen 6T: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Ptch1tm1Mps/Ptch1tm1Mps (more )
Note: This section is at the thoracic level.
Structure Level Pattern Image Note
TS15: neural tube Present Ubiquitous 6T
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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